1212293-24-7 Usage
Uses
Used in Pharmaceutical Industry:
(S)-1-Benzylpyrrolidine-3-carboxylic acid is used as a reactant for the preparation of N-indolylalkyl heteroarylcarboxamide derivatives. These derivatives serve as inhibitors of TAU-induced toxicity, which is a significant factor in the development and progression of neurodegenerative diseases. By targeting TAU-induced toxicity, these derivatives have the potential to provide therapeutic benefits in the treatment of conditions such as Alzheimer's disease, Parkinson's disease, and other related disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 1212293-24-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,2,2,9 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1212293-24:
(9*1)+(8*2)+(7*1)+(6*2)+(5*2)+(4*9)+(3*3)+(2*2)+(1*4)=107
107 % 10 = 7
So 1212293-24-7 is a valid CAS Registry Number.
1212293-24-7Relevant academic research and scientific papers
Thomas, Christoph,Orecher, Florian,Gmeiner, Peter
, p. 1491 - 1496 (1998)
Starting from aspartic acid an efficient synthesis of enantiomerically pure β-proline and homo-β-proline is described. The key step of the synthesis includes formation of the 1,4-biselectrophile 6, followed by rearrangement via the aziridinium intermediate 7 and ring closure to give the pyrrolidinium salt 9a which can serve as a common precursor for both target compounds.
