216311-58-9 Usage
General Description
(S)-Methyl 1-benzylpyrrolidine-3-carboxylate is a chemical compound with the molecular formula C15H19NO2. It is a derivative of pyrrolidine, a five-membered nitrogen-containing heterocycle, and carboxylic acid. (S)-Methyl 1-benzylpyrrolidine-3-carboxylate is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its potential biological activity. It has also been studied for its antihypertensive and anticonvulsant properties. Its unique structure and functional groups make it a versatile building block for the preparation of various organic compounds. Additionally, its stereochemistry makes it an important chiral building block for the preparation of enantiomerically pure chemical compounds. Overall, (S)-Methyl 1-benzylpyrrolidine-3-carboxylate is a valuable chemical compound with diverse applications in the fields of medicine and chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 216311-58-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,6,3,1 and 1 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 216311-58:
(8*2)+(7*1)+(6*6)+(5*3)+(4*1)+(3*1)+(2*5)+(1*8)=99
99 % 10 = 9
So 216311-58-9 is a valid CAS Registry Number.
216311-58-9Relevant articles and documents
Enzymatic resolution of n-substituted-β-prolines
Mendiola, Javier,Garcia-Cerrada, Susana,De Frutos, Oscar,De La Puente, Maria Luz,Gu, Rui Lin,Khau, Vien V.
scheme or table, p. 292 - 296 (2010/04/22)
A general and straightforward strategy for enzymatic resolution of N-substituted-β-proline has been successfully designed and developed in our research laboratories. A first affinity screen is followed by ratio enzyme/substrate optimization to source our
A practical ex-chiral-pool synthesis of β-proline and homo-β-proline
Thomas, Christoph,Orecher, Florian,Gmeiner, Peter
, p. 1491 - 1496 (2007/10/03)
Starting from aspartic acid an efficient synthesis of enantiomerically pure β-proline and homo-β-proline is described. The key step of the synthesis includes formation of the 1,4-biselectrophile 6, followed by rearrangement via the aziridinium intermediate 7 and ring closure to give the pyrrolidinium salt 9a which can serve as a common precursor for both target compounds.
