159063-16-8 Usage
General Description
(S)-1-Benzyl-pyrrolidine-3-carbonitrile is a chemical compound with the molecular formula C13H14N2. It is a pyrrolidine derivative and contains a benzyl group and a carbonitrile functional group. (S)-1-BENZYL-PYRROLIDINE-3-CARBONITRILE is used in various chemical and pharmaceutical applications, often as an intermediate or building block in the synthesis of other organic compounds. Its structure and properties make it useful in the development of new drugs and medications, particularly those targeting the central nervous system and related disorders. It is also studied for potential use in other fields such as materials science and organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 159063-16-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,9,0,6 and 3 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 159063-16:
(8*1)+(7*5)+(6*9)+(5*0)+(4*6)+(3*3)+(2*1)+(1*6)=138
138 % 10 = 8
So 159063-16-8 is a valid CAS Registry Number.
159063-16-8Relevant articles and documents
A practical ex-chiral-pool synthesis of β-proline and homo-β-proline
Thomas, Christoph,Orecher, Florian,Gmeiner, Peter
, p. 1491 - 1496 (2007/10/03)
Starting from aspartic acid an efficient synthesis of enantiomerically pure β-proline and homo-β-proline is described. The key step of the synthesis includes formation of the 1,4-biselectrophile 6, followed by rearrangement via the aziridinium intermediate 7 and ring closure to give the pyrrolidinium salt 9a which can serve as a common precursor for both target compounds.
An Efficient Method for the Synthesis of (R)-3-(1-Amino-1-methylethyl)pyrrolidines for the Antiinfective Agent, PD 138312
Fedij, Victor,Lenoir, Edward A.,Suto, Mark J.,Zeller, James R.,Wemple, James
, p. 1131 - 1134 (2007/10/02)
Methylcerium dichloride has been found to undergo bis addition to nitriles to produce tertiary carbinamines with retention of optical purity at the ? position.This result is used in the development of a short, economical synthesis of the 1,8-naphthyridine antiinfective agent, PD 138312.
