121282-65-3

Upstream product

• 122-60-1 Phenyl glycidyl ether 
• 4648-54-8 trimethylsilylazide 
• 108-95-2 phenol 
• 4769-73-7 (RS)-1-chloro-3-phenyloxy-2-propanol 

Downstream Products

• 140630-37-1 (2R)-1-azido-3-phenoxypropan-2-ol 
• 140630-41-7 (S)-1-azido-3-phenoxy-2-propanol 
• 140630-38-2 (S)-1-azido-2-acetoxy-3-phenoxypropane 
• 4287-19-8 1-amino-3-phenoxy-isopropanol 
• 4698-86-6 3-(3-chlorophenoxy)-2-hydroxypropylamine 

Relevant academic research and scientific papers

Efficient regio- and stereo-selective cleavage of aziridines and epoxides using an ionic liquid as reagent and reaction medium

Ionic liquids, containing a variety of functionalities such as halo, azido, and thiocyano, efficiently cleave aziridines and epoxides to the corresponding products in high yields. The cleavages are regio- and stereo-selective. The reactions are complete i

Green regioselective azidolysis of epoxides catalyzed by multi-site phase-transfer catalyst

A facile synthesis of 1,2-azidoalcohols from their epoxides using α,α',α''-N-hexakis(triethylammoniummethylene chloride)-melamine as amulti-site phase-transfer catalyst in water was developed. By this eco-friendly and highly atom-economic method, a variety of 1,2-azidoalcohols was obtained in high yields with excellent regioselectivity and in short reaction times. Application of this six-site PTC in the ring opening of epoxides by cyanide, acetate and chloride anions was also studied. The catalyst can be recovered after completion of the reaction and can be recycled without affecting the catalytic property.

Polyethylene glycol functionalized magnetic dicationic ionic liquids as a novel catalyst and their application in ring opening of epoxides in water

A simple and environmentally benign protocol for the aqueous synthesis of 1,2-azidoalcohols via regioselective ring opening of 1,2-epoxides using PEG-MDIL as a novel magnetic phase transfer catalyst is described. The catalyst was studied by UV spectroscop

1,1'-bis-methyl-3, 3-methylenebisimidazolium dichloride as an efficient phase transfer catalyst for ring opening of epoxides using SCN- and N 3- in water

An efficient synthesis of β-azido alcohols and β-hydroxy thiocyanates has been achieved by ring opening of epoxides using 1,1'-bis-methyl-3, 3-methylene-bisimidazolium dichloride as a phase transfer catalyst at room temperature in water. The reaction is r

Acetic acid functionalized ionic liquid systems: An efficient and recyclable catalyst for the regioselective ring opening of epoxides with NaN3

In the present study, an environmentally benign, efficient, and solvent-free procedure was developed for the synthesis of 1,2-azidoalcohols by the regioselective ring opening of some epoxides with sodium azide (NaN3) in the presence of an aceti

Efficient metal salt catalyzed azidolysis of epoxides with sodium azide in acetonitrile

A new, simple, efficient, completely anti stereoselective method for the azidolysis of 1,2 epoxides with NaN3 in acetonitrile, by means of metal salts, is described. The use of a non-protic solvent makes this method very competitive with the ot

Synthesis of azidohydrins from epoxides using quaternized amino functionalized cross-linked polyacrylamide as a new polymeric phase-transfer catalyst

Poly[N-(2-aminoethyl)acrylamido]trimethyl ammonium chloride resin was developed as a new polymeric phase-transfer catalyst. This quaternized polyacrylamide-catalyzed the regioselective ring opening of epoxides by azide ion to give azidohydrins in high yie

Ring opening of epoxides and aziridines with sodium azide using Oxone in aqueous acetonitrile: A highly regioselective azidolysis reaction1

A wide variety of epoxides and aziridines were converted to the corresponding β-azido alcohols and β-azido amines with sodium azide using Oxone in aqueous acetonitrile. The reactions were highly regioselective and efficient with excellent yields at room t

Facile synthesis of an organic-inorganic nanocomposite, PEG-silica, by sol-gel method; Its characterization and application as an efficient catalyst in regioselective nucleophilic ring opening of epoxides: Preparation of β-azido alcohols and β-cyanohydrin

The sol-gel method was used for the synthesis of a PEG-silica hybrid. In order to introduce PEG into the cavities of silica gel, first, the bis(3-trimethoxysilylpropyl)-polyethylene glycol precursor was synthesized by the reaction of 3-chloropropyltrimeth

Poly(ethylene glycol) grafted onto dowex resin: An efficient, recyclable, and mild polymer-supported phase transfer catalyst for the regioselective azidolysis of epoxides in water

(Chemical Equation Presented) In this study, an efficient method was designed to graft poly(ethylene glycol) effectively onto commercial Dowex resin. The catalytic efficiency of the copolymer obtained as a new solid-liquid phase transfer catalyst was stud