121671-61-2Relevant articles and documents
METHODE GENERALE D'ACCES AUX TRIFLUOROMETHYLCETONES. 1ere PARTIE: ALKYLATION DIRECTE DU TRIFLUOROACETYLACETATE D'ETHYLE
Aubert, Corinne,Begue, Jean-Pierre,Charpentier-Morize, Micheline,Nee, Gerard,Langlois, Bernard
, p. 361 - 376 (1989)
Alkylation of Ethyl 4,4,4 trifluoroacetylacetate (ETFAA) 1 by alkyl halides presented some typical features.The reaction was very slow and led preferentially to O-alkylated products.However, with activated halides and under some peculiar conditions, it was possible to obtain selectively C-alkylated products 3 and 4 in good yields.