1219089-32-3

Basic information

• Product Name: L-Proline, 3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-diMethylpropyl)-, (3R,4S,5R)-
• Synonyms: L-Proline, 3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-diMethylpropyl)-, (3R,4S,5R)-;(2S,3R,4S,5R)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxylic acid
• CAS NO: 1219089-32-3
• Molecular Formula: C₂₃H₂₂Cl₂F₂N₂O₂
• Molecular Weight: 467.3357864
• Mol File: 1219089-32-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-Proline, 3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-diMethylpropyl)-, (3R,4S,5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Proline, 3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-diMethylpropyl)-, (3R,4S,5R)-(1219089-32-3)
• EPA Substance Registry System: L-Proline, 3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-diMethylpropyl)-, (3R,4S,5R)-(1219089-32-3)

Safety Data

• Hazardous Substances Data: 1219089-32-3(Hazardous Substances Data)

Upstream product

• 85070-48-0 2-fluoro-3-chlorobenzaldehyde 
• 1219086-87-9 (Z)-3-(3-chloro-2-fluorophenyl)-2-(4-chloro-2-fluorophenyl)prop-2-enenitrile 
• 1219086-88-0 tert-butyl (2S,3R,4S,5R)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carboxylate 
• 75279-53-7 2-(4-chloro-2-fluoro-phenyl)acetonitrile 
• 2987-16-8 3,3-dimethylbutyrylaldehyde 
• 1219086-88-0 racemic (2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-( 4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carboxylic acid tert-butyl ester 

Relevant articles and documents

MDM2 DEGRADERS AND USES THEREOF

The present invention relates to compounds and methods useful for the modulation of mouse double minute 2 homolog ("MDM2") protein via ubiquitination and/or degradation by compounds according to the present invention.