1220993-87-2Relevant academic research and scientific papers
Copper-catalysed three-component carboiodination of arynes: Expeditious synthesis of: O -alkynyl aryl iodides
Cao, Wenxuan,Niu, Sheng-Li,Shuai, Li,Xiao, Qing
, p. 972 - 975 (2020)
A copper-catalysed three-component iodoalkynylation reaction of arynes for the expeditious and versatile synthesis of o-alkynyl aryl iodides has been developed. Mechanism research shows that the reaction goes through two steps enabled by copper catalysis: the formation of 1-iodo-2-arylacetylene and the insertion of the aryne into a C(sp)-I bond.
Selanyl and tellanyl electrophiles as a driving force in the construction of sophisticated polyaromatic hydrocarbons
Arsenyan, Pavel,Petrenko, Alla,Belyakov, Sergey
, p. 7247 - 7255 (2021/05/03)
Herein, we report the first examples ofN-polyaromatic compounds bearing up to 13 fused aromatic rings, including 23H-benzo[12,1]tetrapheno[8,9-b]benzo[12,1]tetrapheno[9,8-h]carbazole derivatives. The reaction of selanyl and tellanyl electrophiles with ethynyl biphenyls through 6-endo-digclosure allows construction ofN-polyaromatics in a simple one-pot process under mild reaction conditions in excellent yields.
Br?nsted acid-catalysed hydroarylation of unactivated alkynes in a fluoroalcohol-hydrocarbon biphasic system: Construction of phenanthrene frameworks
Takahashi, Ikko,Fujita, Takeshi,Shoji, Noriaki,Ichikawa, Junji
supporting information, p. 9267 - 9270 (2019/08/08)
Transition metal-free hydroarylation of unactivated alkynes was achieved by combining a Br?nsted acid catalyst and a two-phase solvent system consisting of 1,1,1,3,3,3-hexafluoropropan-2-ol (HFIP) and cyclohexane. This protocol is applicable to a wide variety of 2-alkynylbiaryls which leads to the synthesis of substituted phenanthrenes via 6-endo-selective ring closure. The biphasic system achieves highly efficient ring closure by appropriate separation of cationic intermediates from neutral compounds. The vinyl carbocation intermediates are stabilised in the HFIP phase, while the substrates and products are distributed in the cyclohexane phase to suppress intermolecular side reactions.
