122741-44-0 Usage
Description
2,3,4,6-TETRA-O-BENZYL-BETA-D-GLUCOPYRANOSYL FLUORIDE is a complex organic compound that serves as a valuable carbohydrate building block in the field of synthetic chemistry. It is characterized by its unique structure, which features a glucose molecule with four benzyl groups attached to the hydroxyl groups at the 2, 3, 4, and 6 positions, as well as a fluorine atom at the 1-position. 2,3,4,6-TETRA-O-BENZYL-BETA-D-GLUCOPYRANOSYL FLUORIDE is particularly useful for the synthesis of various pharmacologically active compounds, such as mangiferin, homomangiferin, and neomangiferin.
Uses
Used in Pharmaceutical Industry:
2,3,4,6-TETRA-O-BENZYL-BETA-D-GLUCOPYRANOSYL FLUORIDE is used as a synthetic building block for the preparation of pharmacologically active compounds. Its unique structure allows for the creation of complex molecules with potential therapeutic applications, making it a valuable tool in the development of new drugs.
Used in the Synthesis of Mangiferin, Homomangiferin, and Neomangiferin:
2,3,4,6-TETRA-O-BENZYL-BETA-D-GLUCOPYRANOSYL FLUORIDE is used as a key intermediate in the synthesis of mangiferin, homomangiferin, and neomangiferin. These compounds have been found to possess various biological activities, including anti-inflammatory, antioxidant, and anti-cancer properties. The use of this compound in their synthesis allows for the development of more effective and targeted treatments for a range of diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 122741-44-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,7,4 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 122741-44:
(8*1)+(7*2)+(6*2)+(5*7)+(4*4)+(3*1)+(2*4)+(1*4)=100
100 % 10 = 0
So 122741-44-0 is a valid CAS Registry Number.
InChI:InChI=1/C34H35FO5/c35-34-33(39-24-29-19-11-4-12-20-29)32(38-23-28-17-9-3-10-18-28)31(37-22-27-15-7-2-8-16-27)30(40-34)25-36-21-26-13-5-1-6-14-26/h1-20,30-34H,21-25H2/t30-,31-,32+,33-,34?/m1/s1
122741-44-0Relevant articles and documents
Electrochemical Synthesis of Glycosyl Fluorides Using Sulfur(VI) Hexafluoride as the Fluorinating Agent
Kim, Sungjin,Nagorny, Pavel
, p. 2294 - 2298 (2022/04/07)
This manuscript describes the electrochemical synthesis of 17 different glycosyl fluorides in 73-98% yields on up to a 5 g scale that relies on the use of SF6 as an inexpensive and safe fluorinating agent. Cyclic voltammetry and related mechanistic studies carried out subsequently suggest that the active fluorinating species generated through the cathodic reduction of SF6 are transient under these reductive conditions and that the sulfur and fluoride byproducts are effectively scavenged by Zn(II) to generate benign salts.
Blue Light Photocatalytic Glycosylation without Electrophilic Additives
Wen, Peng,Crich, David
supporting information, p. 2402 - 2405 (2017/05/12)
Photocatalytic formation of glycosidic bonds employing stable and readily accessible O-glycosyl derivatives of 2,2,6,6-tetramethylpiperidin-1-ol is presented that employs an iridium-based photocatalyst and blue LEDs. The reaction proceeds at room temperature and in the absence of additives other than 4 ? molecular sieves. Stereoselectivities are modest but nevertheless dependent on the anomeric configuration of the donor, suggesting a substantial degree of concerted character.
MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS
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Page/Page column 82, (2014/07/08)
The present invention relates to compounds useful for the treatment or prevention of bacteria infections. These compounds have formula (I). The invention also provides pharmaceutically acceptable compositions containing the compounds and methods of using the compositions in the treatment of bacteria infections. Finally, the invention provides processes for making compounds of the invention.
