123217-56-1Relevant articles and documents
Copper-catalyzed aerobic double functionalization of benzylic C(sp3)-H bonds for the synthesis of 3-hydroxyisoindolinones
Nozawa-Kumada, Kanako,Matsuzawa, Yuta,Ono, Kanako,Shigeno, Masanori,Kondo, Yoshinori
supporting information, p. 8604 - 8607 (2021/09/02)
A copper-catalyzed aerobic 3-hydroxyisoindolinone synthesis was developed via the benzylic double C(sp3)-H functionalization of 2-alkylbenzamides. In this reaction, molecular oxygen was used as both an oxidant for C(sp3)-H functionalization and an oxygen source. Our method can be extended to diverse benzylic C(sp3)-H bonds and shows excellent functional group tolerance. This journal is
Reaction of 3-Hydroxyisoindolin-1-ones with Lawesson Reagent. Synthesis of Isoindoline-1-thiones
Nishio, Takehiko,Okuda, Norikazu,Mori, Yo-ichi,Kashima, Choji
, p. 396 - 397 (2007/10/02)
Treatment of 3-hydroxyisoindolin-1-ones 1 with Lawesson reagent gave isoindoline-1-thiones 2, by direct thionation and reductive elimination of hydroxy group, in good yields.
