304477-64-3

Upstream product

• 673-32-5 1-Phenylprop-1-yne 
• 108-90-7 chlorobenzene 
• 93-55-0 1-phenyl-propan-1-one 
• 38512-04-8 N-benzyl(1-phenylpropylidene)amine 
• 1235751-66-2 3-ethyl-3-phenyl-3H-diazirine 
• 1679-18-1 4-Chlorophenylboronic acid 

Downstream Products

• 126866-18-0 1-phenyl-2-(4-chlorophenyl)-propan-1-one 
• 126866-24-8 1-(4-chlorophenyl)-2-phenylpropan-1-one 

Relevant academic research and scientific papers

Metal-free oxidative cross-coupling of diazirines with arylboronic acids

We report herein a metal-free cross-coupling of diazirines with arylboronic acids under oxidative conditions. The reaction affords a series of substituted olefins. It is proposed that the interaction between the nitrogen on diazirine with arylboronic acid plays a key role in this transformation.

Thermodynamically- and kinetically-controlled Friedel-Crafts alkenylation of arenes with alkynes using an acidic fluoroantimonate(v) ionic liquid as catalyst

By employing superacidic fluoroantimonate ionic liquid (IL), [bmim][Sb 2F11], as catalyst, not only thermodynamically-controlled but also kinetically-controlled Friedel-Crafts alkenylations of arenes with alkynes have been realized for the first time. The Royal Society of Chemistry.

Metal triflate-catalyzed regio- And stereoselective friedelCrafts alkenylation of arenes with alkynes in an ionic liquid: Scope and mechanism

In the metal triflate-catalyzed hydroarylation of alkynes, employing an ionic liquid dramatically enhanced the catalytic activities, resulting in broadening the scope of substrates (arenes and alkynes). In some cases, even reactions that were not possible in conventional organic solvents proceeded smoothly in ionic liquids. Moreover, the ionic liquid phase containing catalyst could be readily recovered by simple decantation of the organic layer after reaction and reused for the following runs without any significant loss of activity. Mechanistic studies including 13C NMR analysis of reaction intermediates and isotope experiments confirmed for the first time that this type of reaction proceeds via vinyl cationic intermediates.