124156-27-0

Upstream product

• 124156-21-4 ethyl (4-methoxyphenylimino)acetate 
• 108-12-3 isopentanoyl chloride 
• 104-94-9 4-methoxy-aniline 
• 3350-78-5 3,3-Dimethylacryloyl chloride 
• 124156-27-0 ethyl 3-isopropyl-1-(4-methoxyphenyl)-4-oxoazetidin-2-carboxylate 
• 124156-35-0 1-p-anisyl-3-isopropylidene-4-carbethoxy-2-azetidinone 
• 124156-25-8 cis-1-p-Methoxyphenyl-3-isopropenyl-4-ethoxycarbonylazetidinone 

Downstream Products

• 124156-28-1 cis-3-isopropyl-1-(4-methoxyphenyl)-4-oxoazetidine-2-carboxylic acid 
• 129374-73-8 (3R,4S)-4-Hydroxymethyl-3-isopropyl-1-(4-methoxy-phenyl)-azetidin-2-one 
• 129374-88-5 2-Hydroxy-2-((2S,3R)-3-isopropyl-2-methanesulfonyloxymethyl-4-oxo-azetidin-1-yl)-3-oxo-butyric acid benzyl ester 
• 129374-88-5 2-Hydroxy-2-((2S,3S)-3-isopropyl-2-methanesulfonyloxymethyl-4-oxo-azetidin-1-yl)-3-oxo-butyric acid benzyl ester 
• 136582-28-0 trans-benzyl 3-hydroxy-2-<2-oxo-3-isopropyl-4-(methylsulfonyloxymethyl)azetidin-1-yl>but-2-enoate 
• 136582-28-0 cis-benzyl 3-hydroxy-2-<2-oxo-3-isopropyl-4-(methylsulfonyloxymethyl)azetidin-1-yl>but-2-enoate 
• 129374-68-1 trans-benzyl 7-isopropyl-3-methyl-2-isocephem-4-carboxylate 
• 129374-68-1 cis-benzyl 7-isopropyl-3-methyl-2-isocephem-4-carboxylate 
• 129374-66-9 benzyl (+/-)-trans-7-isopropyl-3-methyl-2-isoxacephem-4-carboxylate 
• 129374-66-9 cis-benzyl 7-isopropyl-3-methyl-2-iso-oxacephem-4-carboxylate 
• 129374-75-0 cis-4-(Hydroxymethyl)-3-isopropyl-1-(4-methoxyphenyl)azetidin-2-one 
• 123003-79-2 1-p-anisyl-3-isopropyl-4-acetoxy-2-azetidinone 
• 82290-87-7 3-isopropyl-4-acetoxy-2-azetidinone 

Relevant academic research and scientific papers

β-Lactam derivatives as enzyme inhibitors: Halogenated β-lactams and related compounds

Different modifications of the imine - acyl chloride reaction were used for the synthesis of 3-mono- and 3,3-dihalogenated 1,4-diaryl substituted β-lactams. Furthermore, these β-lactams were modified by halogen substitution either at the aryl at position

Environmentally benign chemistry: Microwave-induced stereocontrolled synthesis of β-lactam synthons

Microwave irradiation in open glass vessels in unmodified commercial microwave ovens has permitted stereocontrolled synthesis of useful β-lactam synthons not withstanding the fact that the nature of specific activation (if any) of organic reactions by mic

β-Lactams via α,β-Unsaturated Acid Chlorides: Intermediates for Carbapenem Antibiotics

Stereocontrolled synthesis of α-vinyl β-lactams and their transformation to convenient intermediates for PS-5, PS-6, asparenomycin, and thienamycin are described.

Simple and Condensed β-Lactams 12. Alternative Entry into the 2-Isocephem and 2-Iso-oxacephem Series.

The N-Unsubstituted-2-azetidinones ( 17a,b) react smoothly with esters of 2,3-dioxobutyric acid.In resulting intermediates (29b; 30a,b) were converted into the acetoacetates (33b; 34a,b) which were cyclized and deprotected to give the 2-iso-oxacephem- and 2-isocephem-4-carboxylic acids (1a,b) and (2a,b).