124276-65-9

Upstream product

• 654-01-3 (2,6-difluorophenyl)acetonitrile 
• 106-93-4 ethylene dibromide 
• 1489-53-8 1,2,3-trifluorobenzene 
• 5500-21-0 cyclopropropanecarbonitrile 

Downstream Products

• 139229-58-6 1-(2,6-difluorophenyl)cyclopropane-1-carboxylic acid 
• 1346641-12-0 N-(4-cyano-2,3,5,6-tetrafluorophenyl)-1-(2,6-difluorophenyl)cyclopropanecarboxamide 

Relevant academic research and scientific papers

Preparation method of arylcyclopropane compound

The present invention discloses a method for preparing an arylcyclopropane compound, 1.0eq phenylacetonitrile and 1.1eq 1-bromo-2-chloroethane as the starting material, N, N- dimethylacetamide as a solvent, solvent dosage of 10V, plus 2.5eq sodium hydride

Synthesis of 3-oxoesters and functional derivatives of pyrimidin-4(3Н)-one based on 1-(2,6-dihalophenyl)cyclopropan-1-carboxylic acids

Special features of the synthesis and chemical transformations of novel functional derivatives of 6-[1-(2,6-dihalophenyl)cyclopropyl]pyrimidin-4(3H)-one and ethyl esters of 3-[1-(2,6-dihalophenyl)cyclopropyl]-2-methyl-3-oxopropanoic acids prepared from 2-(2,6-dihalophenyl)acetonitriles have been revealed. Novel achiral structural analogs of experimental anti-HIV agent МС-1501 have been synthesized.

PROCESS FOR THE SYNTHESIS OF PROGESTERONE RECEPTOR MODULATORS

Processes for preparing substituted oxindole-2-ones, and specifically the following, are described, wherein R1-R4, R6, and n are defined herein. The processes include reacting a first alkali metal hydroxide, a tetraalkyl a

Process for preparing 3,3-disubstituted oxindoles and thio-oxindoles

Methods for preparing oxindole and thio-oxindole compounds are provided, which compounds are useful as precursors to useful pharmaceutical compounds. Specifically provided are methods for preparing 5-pyrrole-3,3-oxindole compounds and 5-(7-fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile. Also provided are methods for preparing iminobenzo[b]thiophene and benzo[b]thiophenone compounds.

Ortho-substituted benzyl esters of cyclopropanecarboxylic acids

Ortho-substituted benzyl esters of cyclopropanecarboxylic acids I STR1 where X is N or CH and A is one of the following cyclopropane radicals: STR2 where R1 is CN, C2 -C8 -alkyl, CF3, C3 -C8 -alkenyl, (C1 -C4 -alkoxycarbonyl, unsubstituted or substituted phenyl-C1 -C6 -alkyl or phenyl-C3 -C6 -alkenyl, ethoxyphenyl, 2- or 3-bromophenyl, 2- or 4-trifluoromethylphenyl, 2,4- or 2,6-difluorophenyl, 2-fluoro-6-chlorophenyl, 2,4- or 2,6-dimethylphenyl, 2,3,6-trichlorophenyl or trimethylsilyl, R2 is H or halogen, R3 is unsubstituted or substituted phenyl, R4 is CH3 or halogen and Hal is halogen, with the proviso that X is CH when R1 is CF3 or trimethylsilyl, are suitable as fungicides and for controlling pests.