124492-53-1

Basic information

• Product Name: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene] -2'-O-[(1,1-dimethylethyl)dimethylsilyl]-
• CAS NO: 124492-53-1
• Molecular Formula: C40H50N6O6Si
• Molecular Weight: 738.959
• Mol File: 124492-53-1.mol

Chemical Properties

• CAS DataBase Reference: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene] -2'-O-[(1,1-dimethylethyl)dimethylsilyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene] -2'-O-[(1,1-dimethylethyl)dimethylsilyl]-(124492-53-1)
• EPA Substance Registry System: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene] -2'-O-[(1,1-dimethylethyl)dimethylsilyl]-(124492-53-1)

Safety Data

• Hazardous Substances Data: 124492-53-1(Hazardous Substances Data)

Upstream product

• 73793-98-3 5'-O-(4,4'-dimethoxytrityl)-N⁶-dimethylaminomethyleneadenosine 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 68-12-2 N,N-dimethyl-formamide 
• 58-61-7 adenosine 
• 17331-15-6 N⁶-(N,N'-Dimethylaminomethylene)adenosine 

Downstream Products

• 124492-56-4 5'-O-(4,4'-Dimethoxytrityl)-2'-O-tert-butyldimethylsilyl-β-D-xylofuranosyl-N⁶-(N,N'-dimethylaminomethylene)adenine 
• 137760-80-6 C₄₀H₅₁N₆O₈PSi*C₆H₁₅N 
• 124492-54-2 N'-{9-[(2R,3S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3-(tert-butyl-dimethyl-silanyloxy)-4-oxo-tetrahydro-furan-2-yl]-9H-purin-6-yl}-N,N-dimethyl-formamidine 
• 124492-55-3 3-{9-[(2R,3S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3-(tert-butyl-dimethyl-silanyloxy)-4-oxo-tetrahydro-furan-2-yl]-9H-purin-6-yl}-1,1-dimethyl-urea 

Relevant articles and documents

Synthesis of 9-β-D-(Xylofuranosyl)adenine from Adenosine

Protected adenosine 3 was oxidized using Moffatt reagent to give the 3'-ketoadenosine 4 in 60percent yield.Stereospecific reduction of 4 with sodium borohydride in the presence of triethylamine at -18 deg C followed by deprotection effects the inversion o

DIMETHYLAMINOMETHYLENE PROTECTED PURINE H-PHOSPHONATES IN THE SYNTHESIS OF BIOLOGICALLY ACTIVE RNA (24-MER)

Preparation of 5'-O-(4,4'-dimethoxytrityl)-2'-O-tert-butyldimethylsilyl (tBDMSi) derivatives of N2-dimethylaminomethyleneguanosine (IIIa) and N6-dimethylaminomethyleneadenosine (IVa) and their 3'-H-phosphonates (IIIb, IVb) is described.The compounds IIIb and IVb together with corresponding derivatives of uridine (Vb) and N4-benzoylcytidine (VIb) were used as synthones in machine assisted synthesis of microhelixAla (5'-GGGGCUAUAGCUCUAGCU*CCACCA-3')((X).The compound X was aminoacylated by means of alanyl-t-RNA synthetase (E.coli).