124718-87-2Relevant academic research and scientific papers
Synthesis of 1,2-azidoalcohols from epoxides using a task-specific protic ionic liquid: 1-hydrogen-3-methylimidazolium azide
Heidarizadeh, Fariba,Beitsaeed, Ali,Rezaee-Nezhad, Eshagh
, p. 450 - 453 (2014)
A task-specific ionic liquid as an environmentally eco-friendly green catalyst has been synthesized and used in the ring opening of epoxides under green conditions. In order to use protic ionic liquids (PIL), we decided to synthesize 1,2-azidoalcohols via
Organoimido Complexes as a New Class of Lewis Acid Catalysts for Regioselective Ring-Opening of Epoxides
Leung, Wa-Hung,Chow, Ernest K. F.,Wu, Man-Ching,Kum, Polly W. Y.,Yeung, Lam-Lung
, p. 107 - 108 (1995)
Organoimido complexes of Group VI transition metals were found to catalyze ring-opening of epoxides by trimethylsilyl azide and amines with good regioselectivities.
Click chemistry inspired synthesis and bioevaluation of novel triazolyl derivatives of osthol as potent cytotoxic agents
Farooq, Saleem,Shakeel-U-Rehman,Hussain, Aashiq,Hamid, Abid,Qurishi, Mushtaq A.,Koul, Surrinder
, p. 545 - 554 (2014)
A new series of diverse triazoles linked through the hydroxyl group of lactone ring opened osthol (1) were synthesized using click chemistry approach. All the derivatives were subjected to 3-(4,5-Dimethylthiazol-yl)-diphenyl tetrazoliumbromide (MTT) cytot
Fe3O4 nanoparticle-bonded β-cyclodextrin as an efficient and magnetically retrievable catalyst for the preparation of β-azido alcohols and β-hydroxy thiocyanate
Sayyahi, Soheil,Mozafari, Sara,Saghanezhad, Seyyed Jafar
, p. 511 - 518 (2016)
A novel Fe3O4 nanoparticle-bonded β-cyclodextrin (β-CD@MNP) has been synthesized and characterized by scanning electron microscopy, vibrating sample magnetometry, and thermogravimetric analysis. It is found that the nanoparticles can
Glycerol functionalized imidazolium tri-cationic room temperature ionic liquids: Synthesis, properties and catalytic performance for 2-azidoalcohol synthesis from epoxide
Chaugule, Avinash A.,Tamboli, Ashif H.,Sheikh, Faheem A.,Chung, Wook-Jin,Kim, Hern
, p. 314 - 321 (2015)
Imidazolium based tri-cationic room temperature ionic liquid (RTILs) were synthesized and characterized, and their physicochemical properties such as thermal stability, viscosities and solubility were investigated. These ionic liquids exhibited excellent
Do aziridines require Lewis acids for cleavage with ionic nucleophiles?
Bisai, Alakesh,Pandey, Ghanshyam,Pandey, Manoj K.,Singh, Vinod K.
, p. 5839 - 5841 (2003)
A variety of activated aziridines were cleaved by sodium azide and sodium cyanide in aqueous acetonitrile at reflux, in the absence of any Lewis acid, to provide ring-opened products in quantitative yields. However, the reaction was sluggish in the ring o
A hafnium-based metal-organic framework as an efficient and multifunctional catalyst for facile CO2 fixation and regioselective and enantioretentive epoxide activation
Beyzavi, M. Hassan,Klet, Rachel C.,Tussupbayev, Samat,Borycz, Joshua,Vermeulen, Nicolaas A.,Cramer, Christopher J.,Stoddart, J. Fraser,Hupp, Joseph T.,Farha, Omar K.
, p. 15861 - 15864 (2014)
Porous heterogeneous catalysts play a pivotal role in the chemical industry. Herein a new Hf-based metal-organic framework (Hf-NU-1000) incorporating Hf6 clusters is reported. It demonstrates high catalytic efficiency for the activation of epoxides, facilitating the quantitative chemical fixation of CO2 into five-membered cyclic carbonates under ambient conditions, rendering this material an excellent catalyst. As a multifunctional catalyst, Hf-NU-1000 is also efficient for other epoxide activations, leading to the regioselective and enantioretentive formation of 1,2-bifuctionalized systems via solvolytic nucleophilic ring opening.
Me3SI-promoted chemoselective deacetylation: a general and mild protocol
Gurawa, Aakanksha,Kashyap, Sudhir,Kumar, Manoj
, p. 19310 - 19315 (2021/06/03)
A Me3SI-mediated simple and efficient protocol for the chemoselective deprotection of acetyl groups has been developedviaemploying KMnO4as an additive. This chemoselective deacetylation is amenable to a wide range of substrates, tolerating diverse and sensitive functional groups in carbohydrates, amino acids, natural products, heterocycles, and general scaffolds. The protocol is attractive because it uses an environmentally benign reagent system to perform quantitative and clean transformations under ambient conditions.
Carbon isotope labeling of carbamates by late-stage [11C], [13C] and [14C]carbon dioxide incorporation
Del Vecchio, Antonio,Talbot, Alex,Caillé, Fabien,Chevalier, Arnaud,Sallustrau, Antoine,Loreau, Olivier,Destro, Gianluca,Taran, Frédéric,Audisio, Davide
supporting information, p. 11677 - 11680 (2020/10/19)
A general procedure for the late-stage [11C], [13C] and [14C]carbon isotope labeling of cyclic carbamates is reported. This protocol allows the incorporation of carbon dioxide, the primary source of carbon-14 and carbon-11 radioisotopes, in a direct, cost-effective and sustainable manner. A disconnection/reconnection strategy, involving ring opening/isotopic closure, was also implemented.
Concurrent Formation of N-H Imines and Carbonyl Compounds by Ruthenium-Catalyzed C-C Bond Cleavage of β-Hydroxy Azides
Lee, Jeong Min,Bae, Dae Young,Park, Jin Yong,Jo, Hwi Yul,Lee, Eunsung,Rhee, Young Ho,Park, Jaiwook
supporting information, p. 4608 - 4613 (2020/06/05)
A commercial cyclopentadienylrutenium dicarbonyl dimer ([CpRu(CO)2]2) efficiently catalyzes the formation of N-H imines and carbonyl compounds simultaneously from β-hydroxy azides via C-C bond cleavage under visible light. Density functional theory calculations for the cleavage reaction support the mechanism involving chelation of alkoxy azide species and liberation of nitrogen as the driving force. The synthetic utility of the reaction was demonstrated by a new amine synthesis promoted by chemoselective allylation of imine and synthesis of isoquinoline.
