Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1249-67-8

1249-67-8 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 1249-67-8 Structure

  • Basic information

    1. Product Name: 17-hydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate
    2. Synonyms: 21-Acetyloxy-17-hydroxypregna-1,4-diene-3,20-dione
    3. CAS NO:1249-67-8
    4. Molecular Formula: C23H30O5
    5. Molecular Weight: 386.4813
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1249-67-8.mol
    9. Article Data: 5

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 540.5°C at 760 mmHg
    3. Flash Point: 183.8°C
    4. Appearance: N/A
    5. Density: 1.22g/cm3
    6. Vapor Pressure: 6.13E-14mmHg at 25°C
    7. Refractive Index: 1.572
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 17-hydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate(CAS DataBase Reference)
    11. NIST Chemistry Reference: 17-hydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate(1249-67-8)
    12. EPA Substance Registry System: 17-hydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate(1249-67-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1249-67-8(Hazardous Substances Data)

1249-67-8 Usage

Description

17-hydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate, also known as hydrocortisone acetate, is a synthetic steroid hormone derivative belonging to the class of corticosteroids. It possesses anti-inflammatory, immunosuppressive, and anti-allergic properties, making it a valuable pharmaceutical ingredient in various medications.

Uses

Used in Pharmaceutical Industry:
17-hydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate is used as an active pharmaceutical ingredient for the treatment of conditions such as eczema, dermatitis, and allergic reactions. It is effective in reducing inflammation and suppressing the immune response, providing relief to affected individuals.
Used in Topical Medications:
In the form of creams, ointments, and topical solutions, 17-hydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate is used as a local treatment applied directly to the affected area of the skin. This allows for targeted relief and minimizes systemic side effects associated with oral corticosteroids.

Check Digit Verification of cas no

The CAS Registry Mumber 1249-67-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,4 and 9 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1249-67:
(6*1)+(5*2)+(4*4)+(3*9)+(2*6)+(1*7)=78
78 % 10 = 8
So 1249-67-8 is a valid CAS Registry Number.

1249-67-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

1.2 Other means of identification

Product number -
Other names UNII-1N587LS3RF

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1249-67-8 SDS

1249-67-8Relevant articles and documents

Sokolova et al.

, (1972)

-

Rosenkranz et al.

, p. 4081,4084 (1950)

-

Synthesis of the corticoid side chain from 17α-(haloethynyl)-17β-(nitrooxy)androstenes

Hofmeister,Annen,Laurent,Wiechert

, p. 423 - 426 (2007/10/02)

-

Process and intermediates for the preparation of 17 alphahydroxyprogesterones and corticoids from an enol steroid

-

, (2008/06/13)

This invention discloses an improved process for the production of corticoids from 17α-hydroxy steroids utilizing peroxymonosulfate.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1249-67-8