125114-77-4

Basic information

• Product Name: 7-Bromo-1-indanone
• Synonyms: 7-bromo-2,3-dihydroinden-1-one;7-bromo-2,3-dihydro-1H-inden-1-one;7-Bromo-2,3-dihydro-1H-inden-1-one, 7-Bromo-2,3-dihydro-1-oxo-1H-indene;-broMo-2,3-dihydroinden-1-one;1H-Inden-1-one,7-broMo-2,3-dihydro-
• CAS NO: 125114-77-4
• Molecular Formula: C₉H₇BrO
• Molecular Weight: 211.05
• Mol File: 125114-77-4.mol
• Article Data: 14

Chemical Properties

• Melting Point: 114 °C
• Boiling Point: 306.5 °C at 760 mmHg
• Flash Point: 122.2 °C
• Appearance: /
• Density: 1.608 g/cm³
• Vapor Pressure: 0.00077mmHg at 25°C
• Refractive Index: 1.622
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 7-Bromo-1-indanone(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Bromo-1-indanone(125114-77-4)
• EPA Substance Registry System: 7-Bromo-1-indanone(125114-77-4)

Safety Data

• Hazardous Substances Data: 125114-77-4(Hazardous Substances Data)

Usage

General Description

7-Bromo-1-indanone is a chemical compound with the molecular formula C9H7BrO. It is a white to off-white crystalline solid that is used in organic synthesis and pharmaceutical research. 7-Bromo-1-indanone is known for its aromatic properties and is utilized as an intermediate in the production of various pharmaceuticals and pesticides. 7-Bromo-1-indanone is also used as a reagent in the preparation of other organic compounds and is an important building block in the synthesis of diverse chemical products. It is important to handle this compound with caution as it may present hazards if not used properly.

InChI:InChI=1/C9H7BrO/c10-7-3-1-2-6-4-5-8(11)9(6)7/h1-3H,4-5H2

Upstream product

• 71126-19-7 2-bromophenyl-2-chloroethyl ketone 
• 628732-03-6 7-amino-2,3-dihydro-1H-inden-1-one 
• 3132-99-8 m-bromobenzoic aldehyde 
• 88-65-3 2-bromobenzoic-acid 
• 83-33-0 inden-1-one 
• 681246-49-1 6-amino-7-bromo-2,3-dihydro-1H-inden-1-one 
• 71095-56-2 1-(2-bromophenyl)-2-propen-1-one 
• 6351-10-6 1-Indanol 
• 1196049-18-9 rac-7-bromo-2,3-dihydro-1H-inden-1-ol 
• 7154-66-7 2-bromobenzoic acid chloride 
• 754-05-2 ethenyltrimethylsilane 
• 77802-37-0 N-(2,3-dihydro-1H-inden-4-yl)acetamide 
• 32202-61-2 4-aminoindan 
• 58161-36-7 N-(3-oxo-2,3-dihydro-1H-inden-4-yl)acetamide 

Downstream Products

• 1071449-08-5 7-bromo-2,3-dihydro-1H-inden-1-amine 
• 1311994-30-5 C₂₆H₂₄N₂O₄S 
• 1311994-26-9 ethyl 3-(3-(tert-butoxycarbonylamino)-2,3-dihydro-1H-inden-4-yl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate 

Relevant articles and documents

Metallocene compound, catalyst component for olefin polymerization and catalyst for olefin polymerization containing the same, and method for producing olefin polymer using catalyst for olefin polymerization

The metallocene compound represented by the following general formula (1): (the numerals and signs in the general formula (1) are as described in the description).

Novel synthetic method for 7-halogen-1-indanone

The invention discloses a novel synthetic method for 7-halogen-1-indanone. The reaction general formula of the method is shown in the description, wherein X is fluorine, chlorine or bromine. The method provided by the invention uses o-halogenated acetophenone as a starting raw material, an iron-catalyzed carbonyl methylenation reaction is performed to obtain a vinyl ketone, and acid-catalyzed ringclosure is performed to obtain the 7-halogen-1-indanone. The method provided by the invention has the advantages that the raw materials are simple and easy to obtain, the post-treatment is simple andthe total yield is high, and can provide an important reference for industrialized production.

SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE

Compounds having a structure of Formula (IX) or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R1, R2a, R2b, R3a, R3b, R4a, R4b, Q1----Q2, R6, R7, A, B, W, x, and y are as defined herein and are provided. Pharmaceutical compositions comprising such compounds and methods for treating various HAT-related conditions or diseases, including cancer, by administration of such compounds are also provided.