125220-94-2

Basic information

• Product Name: METHOXYPOLYETHYLENE GLYCOL 5,000 PROPIONIC ACID
• Synonyms: O-(2-CARBOXYETHYL)-O'-METHYLPOLYETHYLENE GLYCOL 5,000;MONO-METHYL POLYETHYLENE GLYCOL 5'000 PROPIONIC ACID;METHOXYPOLYETHYLENE GLYCOL 5,000 PROPIONIC ACID;METHOXYPOLY(ETHYLENE GLYCOL) PROPIONIC ACID;mono-Methyl polyethylene glycol 5μ000 propionic acid, O-(2-Carboxyethyl)-Oμ-methylpolyethylene glycol 5,000;m-PEG12-acid;m-PEG16-acid;m-PEG24-acid
• CAS NO: 125220-94-2
• Molecular Formula: MeO-PEG-C2H4CO2H
• Molecular Weight: 0
• Mol File: 125220-94-2.mol

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: METHOXYPOLYETHYLENE GLYCOL 5,000 PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: METHOXYPOLYETHYLENE GLYCOL 5,000 PROPIONIC ACID(125220-94-2)
• EPA Substance Registry System: METHOXYPOLYETHYLENE GLYCOL 5,000 PROPIONIC ACID(125220-94-2)

Safety Data

• WGK Germany: 3
• F: 10-23
• Hazardous Substances Data: 125220-94-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
METHOXYPOLYETHYLENE GLYCOL 5,000 PROPIONIC ACID is used as a molecular linker for the conjugation of therapeutic agents, such as drugs or proteins, to improve their solubility, stability, and bioavailability in aqueous environments. The formation of stable amide bonds with primary amine groups allows for the creation of drug conjugates with enhanced pharmacokinetic properties and reduced immunogenicity.
Used in Drug Delivery Systems:
In the field of drug delivery, METHOXYPOLYETHYLENE GLYCOL 5,000 PROPIONIC ACID serves as a key component in the design of targeted drug delivery systems. The hydrophilic PEG spacer can be utilized to enhance the solubility and circulation time of drug-loaded nanoparticles or liposomes, while the reactive carboxylic acid group allows for the attachment of targeting ligands or drugs to the delivery system. This enables the development of more effective and selective therapies with reduced side effects.
Used in Bioconjugation:
METHOXYPOLYETHYLENE GLYCOL 5,000 PROPIONIC ACID is used as a bioconjugation agent for the attachment of various biomolecules, such as antibodies, peptides, or enzymes, to other molecules or surfaces. The stable amide bond formation with primary amine groups enables the creation of bioconjugates with well-defined structures and improved performance in biological applications, such as immunoassays, sensors, or drug discovery.
Used in Material Science:
In the field of material science, METHOXYPOLYETHYLENE GLYCOL 5,000 PROPIONIC ACID can be employed as a functional component in the development of hydrogels, coatings, or other materials with tailored properties. The hydrophilic PEG spacer and reactive carboxylic acid group can be used to modify the surface properties of materials, enhance their biocompatibility, or introduce specific functionalities, such as drug release or cell adhesion.

Upstream product

• 109-86-4 2-methoxy-ethanol 
• 140-88-5 ethyl acrylate 
• 112-35-6 triethylene glucol monomethyl ether 
• 292638-85-8 acrylic acid methyl ester 
• 1197154-62-3 ethyl 2,5,8,11,14-pentaoxaheptadecan-17-oate 
• 23783-42-8 tetraethylene glycol monomethyl ether 
• 23601-40-3 hexaethylene glycol monomethyl ether 
• 874208-90-9 tert-butyl 2,5,8,11,14,17,20-heptaoxatricosan-23-oate 
• 874208-93-2 3-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-propionic acid tert-butyl ester 
• 111-77-3 2-(2-methoxyethoxy)ethyl alcohol 
• 1663-39-4 tert-Butyl acrylate 
• 1778219-81-0 tert-butyl 3-[2-(2-methoxyethoxy)ethoxy]propanoate 
• 883554-11-8 tert-butyl 2,5,8,11-tetraoxatetradecan-14-oate 

Downstream Products

• 1360551-17-2 5-(4-{1-[5-(2-methoxy-ethoxymethyl)-[1,2,4]oxadiazol-3-yl]-1,2-dimethyl-propyl}-phenyl)-pyrimidin-2-ylamine 
• 1313867-65-0 C₂₄H₃₈Br₂N₂O₁₀ 
• 1313867-66-1 C₃₄H₅₆N₂O₁₀Si₂ 
• 1313867-68-3 C₂₈H₄₀N₂O₁₀ 
• 1313867-67-2 C₃₁H₄₈N₂O₁₀Si 
• 1313867-69-4 C₅₃H₈₀N₂O₂₀Si 
• 1313867-70-7 C₅₀H₇₂N₂O₂₀ 
• 1429340-14-6 1-(4-(2-(5-((4-2,5,8,11-tetraoxatetradecanepiperazin-1-yl)methyl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-3-cyclopropylurea 
• 622405-78-1 triethylene glycol monomethyl ether propionic acid-N-succinimidyl ester 
• 874208-94-3 1-[(17-oxo-2,5,8,11,14-pentaoxaheptadecan-17-yl)oxy]pyrrolidine-2,5-dione 
• 874208-92-1 3-{2-[2-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 1333318-14-1 C₁₅H₂₄NO₇P 

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