1253286-56-4 Usage
Uses
Used in Biomedical Research:
Biotin-PEG3-NHS ester is used as a biotinylation agent for the modification of proteins, enabling their detection, purification, and immobilization on various surfaces. This application is crucial in various biomedical research areas, including protein-protein interaction studies, enzyme-linked immunosorbent assays (ELISA), and the development of biosensors.
Used in Drug Development:
In the pharmaceutical industry, Biotin-PEG3-NHS ester is used as a bioconjugation tool for the development of targeted drug delivery systems. By attaching biotinylated molecules to drug carriers, researchers can enhance the specificity and efficiency of drug delivery, potentially improving therapeutic outcomes and reducing side effects.
Used in Diagnostics:
Biotin-PEG3-NHS ester is employed as a key component in the development of diagnostic tools, such as lateral flow assays and immunoassays. The biotinylated proteins or other biomolecules can be easily detected using streptavidin-conjugated detection systems, allowing for rapid and sensitive detection of target analytes.
Used in Material Science:
In the field of material science, Biotin-PEG3-NHS ester is used for the functionalization of surfaces, such as microfluidic devices and sensors. The biotinylated surfaces can be further modified with specific ligands or receptors, enabling the capture and analysis of target molecules, which is essential for various analytical and diagnostic applications.
Used in Cell Biology:
Biotin-PEG3-NHS ester is utilized in cell biology for the labeling and tracking of proteins within living cells. By biotinylating proteins of interest, researchers can study their localization, dynamics, and interactions within the cellular environment, providing valuable insights into cellular processes and mechanisms.
Physical Form
Solid
storage
Store at or below ≤4°C. Solid form is stable at least 2 years from date of receipt, when stored as directed.
Check Digit Verification of cas no
The CAS Registry Mumber 1253286-56-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,3,2,8 and 6 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1253286-56:
(9*1)+(8*2)+(7*5)+(6*3)+(5*2)+(4*8)+(3*6)+(2*5)+(1*6)=154
154 % 10 = 4
So 1253286-56-4 is a valid CAS Registry Number.
1253286-56-4Relevant academic research and scientific papers
SYNTHESIS OF NOVEL ASYMMETRIC BOW-TIE PAMAM DENDRIMER-BASED CONJUGATES FOR TUMOR-TARGETING DRUG DELIVERY
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, (2015/03/28)
The present disclosure relates to a dendrimer-based conjugate of the formula Vm-D-C-D'-(T-F)n, which is useful for tumor targeting drug delivery. The use of asymmetric dendrimers allow for specific targeting as well as synthetic reproducibility.