1254069-39-0

Basic information

• Product Name: 6-nitro-1-phenyl-2,3-dihydro-1H-indazol-3-one
• Synonyms: 6-nitro-1-phenyl-2,3-dihydro-1H-indazol-3-one
• CAS NO: 1254069-39-0
• Molecular Weight: 255.233
• Mol File: 1254069-39-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 6-nitro-1-phenyl-2,3-dihydro-1H-indazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-nitro-1-phenyl-2,3-dihydro-1H-indazol-3-one(1254069-39-0)
• EPA Substance Registry System: 6-nitro-1-phenyl-2,3-dihydro-1H-indazol-3-one(1254069-39-0)

Safety Data

• Hazardous Substances Data: 1254069-39-0(Hazardous Substances Data)

Upstream product

• 25938-95-8 2-chloro-4-nitrobenzoic acid N'-phenylhydrazide 
• 99-60-5 2-chloro-4-nitrobenzoic acid 
• 100-63-0 phenylhydrazine 
• 63480-10-4 4-nitroisatoic anhydride 
• 619-17-0 4-Nitroanthranilic acid 
• 67571-10-2 2-amino-4-nitro-N'-phenylbenzohydrazide 

Downstream Products

• 1254069-38-9 3-(methylthio)-1-phenyl-1H-indazol-6-amine 
• 1254069-41-4 4-(3-methylsulfanyl-1-phenyl-1H-indazol-6-ylcarbamoyl)piperidine-1-carboxylicacid tert-butyl ester 
• 1254069-36-7 N-(3-(methylthio)-1-phenyl-1H-indazol-6-yl)piperidine-4-carboxamide hydrochloride 
• 1254069-40-3 3-(methylthio)-6-nitro-1-phenyl-1H-indazole 
• 1345403-98-6 3-(3-Methylsulfanyl-1-phenyl-1H-indazol-6-ylcarbamoyl)-azetidine-1-carboxylic acid tert-butyl ester 
• 1332526-66-5 N-(3-(methylthio)-1-phenyl-1H-indazol-6-yl)pyrrolidine-3-carboxamide 
• 1332526-67-6 N-(3-(methylthio)-1-phenyl-1H-indazol-6-yl)azetidine-3-carboxamide 
• 1332526-69-8 N-(3-methylsulfanyl-1-phenyl-1H-indazol-6-yl)-3-(piperazin-1-yl)propionamide 
• 1332526-65-4 N-(3-(methylthio)-1-phenyl-1H-indazol-6-yl)piperidine-3-carboxamide 
• 1345404-00-3 2-[(3-Methylsulfanyl-1-phenyl-1H-indazol-6-ylcarbamoyl)-methyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 1345404-92-3 3-methoxy-6-nitro-1-phenyl-1H-indazole 
• 1345404-93-4 3-methoxy-1-phenyl-1H-indazol-6-ylamine 
• 1345404-02-5 3-[3-(3-Methylsulfanyl-1-phenyl-1H-indazol-6-yl)-ureido]-pyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Copper-catalyzed synthesis of substituted indazoles from 2-chloroarenes at low catalyst-loading

An efficient and convenient access to 1-substituted indazol-3-ones 2 has been achieved throughout the intramolecular C-N bond formations of 2-chloro-benzoic acid-N′-aryl and alkyl-hydrazides employing 0.5 mol% of cuprous (I) iodide and 20 mol% of l-prolin

INDAZOLE COMPOUNDS USEFUL AS KETOHEXOKINASE INHIBITORS

The present invention is directed to substituted indazole compounds, pharmaceutical compositions of these compounds and methods of use thereof. The compounds of the present invention are ketohexokinase (KHK) inhibitors, useful for treating or ameliorating a KHK mediated metabolic disorders and/or diseases such as obesity, Type II diabetes mellitus and Metabolic Syndrome X.