1256258-90-8Relevant academic research and scientific papers
Plasma-mediated release of morphine from synthesized prodrugs
Thomas, Thommey P.,Huang, Baohua,Desai, Ankur,Zong, Hong,Cheng, Xue-Min,Kotlyar, Alina,Leroueil, Pascale R.,Dunham, Thomas,Van Der Spek, Abraham,Ward, Brent B.,Baker Jr., James R.
, p. 6250 - 6253 (2010)
Two morphine prodrugs ('PDA' and 'PDB') were synthesized and the kinetics of esterase-mediated morphine release from these prodrugs were determined when incubated with plasma from different animal species. Morphine was rapidly released from PDA by all spe
BENZODICYCLOALKANE DERIVATIVE, PREPARATION METHOD AND USE THEREOF
-
Paragraph 0154; 0500; 0505, (2019/06/19)
It is provided herein a benzobicycloalkane derivative, and a preparation method and use thereof. In particular, it is provided herein a compound of Formula (I), or a pharmaceutically acceptable salt, stereoisomer or solvate thereof, a preparation method, and a use thereof in preparation of drugs for treating pain.
