1257863-91-4

Upstream product

• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 1036403-99-2 (R)-2-[(N-benzyloxycarbonyl)piperidin-2-yl]ethanoic acid 
• 501-53-1 benzyl chloroformate 
• 542-05-2 acetonedicarboxylic acid 
• 1369774-33-3 (1R,5R)-9-benzyloxycarbonylamino-2-oxo-1-oxabicyclo[3.3.1]nonane 
• 1369774-32-2 7-benzyloxycarbonylazabicyclo-[3.2.1]octan-6-one 
• 1369774-31-1 (1R,5S,6S)-N-benzyloxycarbonyl-6-tropanol 
• 1369774-30-0 (1R,5S,6R)-6-tropanol 
• 1369774-34-4 (1R,5S,6R)-6-tropanol (R,R)-tartrate 
• 1369774-29-7 6-tropanol 

Downstream Products

• 212556-93-9 benzyl (2R)-2-(2-oxopentyl)piperidine-1-carboxylate 
• 2858-66-4 (-)-pelletierine 
• 184535-06-6 (+)-(2R)-(2-oxopropyl)piperidine-1-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Syntheses of (-)-pelletierine and (-)-homopipecolic acid

Enantiomeric syntheses of (-)-homopipecolic acid and (-)-pelletierine have been achieved by chiral resolution of tropanol followed by Baeyer-Villiger oxidation. The methodology provides a practical route for the synthesis of optically pure piperidines. The Royal Society of Chemistry 2012.

Hydroformylation of alkenylamines. Concise approaches toward piperidines, quinolizidines, and related alkaloids

Linear hydroformylation of N-protected allyl- or homoallylamines (cyclohydrocarbonylation: CHC), followed by a reductive amination constitute the two key steps toward convenient routes to aza-heterocycles.