1369774-33-3

Upstream product

• 501-53-1 benzyl chloroformate 
• 542-05-2 acetonedicarboxylic acid 
• 1369774-31-1 (1R,5S,6S)-N-benzyloxycarbonyl-6-tropanol 
• 1369774-30-0 (1R,5S,6R)-6-tropanol 
• 1369774-34-4 (1R,5S,6R)-6-tropanol (R,R)-tartrate 
• 1369774-29-7 6-tropanol 

Downstream Products

• 1257863-91-4 benzyl (2R)-2-(2-(methoxy(methyl)amino)-2-oxoethyl)piperidine-1-carboxylate 
• 19832-04-3 (R)-2-(piperidin-2'-yl)ethanoic acid 
• 184535-06-6 (+)-(2R)-(2-oxopropyl)piperidine-1-carbamic acid benzyl ester 
• 2858-66-4 (-)-pelletierine 
• 1036403-99-2 (R)-2-[(N-benzyloxycarbonyl)piperidin-2-yl]ethanoic acid 

Relevant academic research and scientific papers

Synthesis of dendrobatid alkaloid (+)-167B and (+)-209D and the investigation of diastereoselectivity using DFT calculations

The synthesis of dendrobatid alkaloid (+)-167B and (+)-209D has been developed on the basis of the effective preparation of chiral tropinone 7-azabicyclo[3.2.1]octan-6-ol. DFT calculations have been applied to explain the observed diastereoselectivity.

Syntheses of (-)-pelletierine and (-)-homopipecolic acid

Enantiomeric syntheses of (-)-homopipecolic acid and (-)-pelletierine have been achieved by chiral resolution of tropanol followed by Baeyer-Villiger oxidation. The methodology provides a practical route for the synthesis of optically pure piperidines. The Royal Society of Chemistry 2012.