125968-55-0

Upstream product

• 105782-42-1 (2RS,3SR)-2,3-epoxy-1-(4-methoxyphenyl)-3-(4-methoxyphenyl)propan-1-one 
• 124-46-9 guanidine hydrogen carbonate 
• 41564-67-4 (E)-1,3-bis(4-methoxyphenyl)-2-propene-1-one 
• 3319-15-1 rac-1-(4-methoxyphenyl)-ethanol 
• 113-00-8 guanidine nitrate 
• 105-13-5 4-Methoxybenzyl alcohol 
• 2373-89-9 4,4'-dimethoxychalcone 
• 1000385-94-3 C₁₁H₁₀N₃ClSO₃ 
• 5720-07-0 4-methoxyphenylboronic acid 
• 123-11-5 4-methoxy-benzaldehyde 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 50-01-1 guanidine hydrochloride 
• 56-05-3 2-Amino-4,6-dichloropyrimidine 

Downstream Products

• 24030-15-7 4,6-bis(4-methoxyphenyl)pyrimidin-2-ol 
• 1226781-10-7 C₃₃H₃₆N₄O₁₁S 
• 125968-57-2 5-amino-4,6-bis(p-methoxyphenyl)pyrimidine 
• 125968-56-1 5-nitroso-4,6-bis(p-methoxyphenyl)pyrimidine 

Relevant academic research and scientific papers

A green approach for the synthesis of benzazolyl pyrimidinyl carbamothioates under ultrasonication and their antimicrobial activity

A library of benzazolyl pyrimidinyl carbamothioates were prepared by the reaction of benzazolyl carbonothioates with pyrimidinyl-2-amine in the presence of an ionic liquid- 1-butyl-3-methylimidazolium hydroxide ([bmim]OH) under ultrasonication at a frequency of 35?kHz and tested for antimicrobial activity. Chloro- and nitro-substituted benzothiazolyl/benzimidazolyl pyrimidinyl carbamothioates displayed prominent antibacterial activity against Bacillus subtilis, while nitro-substituted benzothiazolyl/benzimidazolyl pyrimidinyl carbamothioates showed excellent antifungal activity against Aspergilus niger. Graphic abstract: [Figure not available: see fulltext.].

Design and synthesis of quinoline-pyrimidine inspired hybrids as potential plasmodial inhibitors

Presently, artemisinin-based combination therapy (ACT) is the first-line therapy of Plasmodium falciparum malaria. With the emergence of malaria parasites that are resistant to ACT, alternative antimalarial therapies are urgently needed. In line with this

Iron Catalyzed Synthesis of Pyrimidines Under Air

Herein we report an iron-catalyzed multicomponent dehydrogenative functionalization of alcohols to pyrimidines under atmospheric conditions. Using a well-defined Fe(II)-complex featuring redox noninnocent 2-phenylazo-(1,10-phenanthroline) ligand, as a cat

Mechanistic investigations on substituted benzene sulphonamides as apoptosis inducing anticancer agents

In an approach to develop potent cytotoxic compounds with targeted action, a systematic methodology was employed to design and initially synthesize parent compounds A1, A8, A13 and A14 followed by synthesis of further analogs of A1 (A2-A7) and A8 (A9-A12)

Influence of the C-5 substitution in polysubstituted pyrimidines on inhibition of prostaglandin E2 production

As a part of a broader structure-activity relationship study of substituted 2-aminopyrimidines, the influence of the C-5 substitution on inhibition of prostaglandin E2 (PGE2) production was studied. Thirty compounds were prepared sta

Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists

Two regioisomeric series of diaryl 2- or 4-amidopyrimidines have been synthesized and their adenosine receptor affinities were determined in radioligand binding assays at the four human adenosine receptors (hARs). Some of the ligands prepared herein exhib

2-Amino-6-iodo-4-tosyloxypyrimidine: a versatile key intermediate for regioselective functionalization of 2-aminopyrimidines in 4- and 6-positions

2-Amino-6-iodo-4-tosyloxypyrimidine, easily prepared from commercially available material, is a key intermediate for the preparation of differentially substituted 2-aminopyrimidines by means of sequenced Suzuki and/or Sonogashira reactions.

Synthesis of N-Heterocycles via Chalcone Epoxides. 1. Amino and Hydrazinopyrimidines

Chalcone epoxides have been used as precursors in the synthesis of 2-amino- and 2-hydrazinopyrimidines.