127060-83-7

Upstream product

• 119433-11-3 (1R,2R,3R,5R,8R)-(+)-8-Benzoyloxy-2,7,7-trimethylbicyclo<3.3.0>octan-3-ol 
• 90546-11-5 (3aRS,6SR,6aRS)-1-chloromethyl-3,3a,4,5,6,6a-hexahydro-6-hydroxy-5,5-dimethylpentalene 
• 78-88-6 2,3-Dichloroprop-1-ene 
• 82881-09-2 6α-benzoyloxy-4β,7,7-trimethyl-1α,5α-bicyclo<3.3.0>octan-3-one 
• 74552-31-1 (6R,7R)-(-)-7-Hydroxy-3-oxabicyclo<4.3.0>non-1-en-9-on 
• 127060-82-6 (1R,3aR,6R,6aR)-(+)-6-(Benzoyloxy)-3,3a,4,5,6,6a-hexahydro-1,5,5-trimethyl-2(1H)-pentalenon 
• 90546-13-7 (1RS,2RS,3aRS,6RS,6aRS)-6-benzoyloxy-octahydro-2-hydroxy-1,5,5-trimethylpentalene 
• 69478-28-0 (1R,3aR,6aS)-6-Hydroxymethyl-2,2-dimethyl-1,2,3,3a,4,6a-hexahydro-pentalen-1-ol 
• 69478-30-4 (1R,3aS,6aR)-2,2,6-Trimethyl-1,2,3,3a,4,6a-hexahydro-pentalen-1-ol 
• 69478-30-4 (3aRS,6SR,6aRS)-3,3a,4,5,6,6a-hexahydro-6-hydroxy-1,5,5-trimethylpentalene 
• 90546-12-6 (3aRS,6RS,6aRS)-6-benzoyloxy-3,3a,4,5,6,6a-hexahydro-1,5,5-trimethylpentalene 
• 82873-78-7 (3aRS,6SR,6aRS)-3,3a,4,5,6,6a-hexahydro-6-methanesulfonyloxy-1,5,5-trimethylpentalene 
• 90546-09-1 cis-3,3a,4,5,6,6a-hexahydro-5,5-dimethyl-6-oxo-1-pentalenecarboxylic acid methyl ester 
• 82873-74-3 (2aSR,4RS,4aSR,6aSR,6bRS)-octahydro-6,6-dimethyl-2-oxo-2H-pentaleno<1,6-bc>furan-4-carboxylic acid 

Downstream Products

• 80677-96-9 (-)-Hypnophilin 
• 127001-14-3 (3aS,3bR,4R,6aS)-(-)-6-(Benzoyloxy)-3,3a,3b,4,5,6,6a,7-octahydro-3a,5,5-trimethyl-2H-cyclopentapentalen-2-on 
• 82873-85-6 (3aR,3bS,4S,6aR,7R)-7-Hydroxy-3,3a,5,5-tetramethyl-3-phenylselanyl-4-(tetrahydro-pyran-2-yloxy)-3,3a,3b,4,5,6,6a,7-octahydro-cyclopenta[a]pentalen-2-one 
• 85031-56-7 (3aR,3bS,4S,6aR,7R)-3,3a,5,5-Tetramethyl-3-phenylselanyl-4,7-bis-(tetrahydro-pyran-2-yloxy)-3,3a,3b,4,5,6,6a,7-octahydro-cyclopenta[a]pentalen-2-one 
• 82873-82-3 (1SR,3aRS,6RS,6aRS)-1-acetonyl-6-benzoyloxy-1,3a,4,5,6,6a-hexahydro-1,5,5-trimethyl-2(3H)-pentalenone 
• 127060-84-8 (1S,3aR,6R,6aR)-(-)-6-Benzoyloxy-3,3a,4,5,6,6a-hexahydro-1,5,5-trimethyl-1-(2-oxopropyl)-2(1H)-pentalenon 

Relevant academic research and scientific papers

Chemistry and Stereochemistry of Iridoids, XVI. - EPC-Synthesis of (-)-Hypnophilin

The synthesis of enantiomerically pure (-)-hypnophilin (27) from (6R,7R)-(-)-7-hydroxy-3-oxabicyclonon-1-en-9-one (1) is described. 1 was obtained in 93 percent yield from catalpol, which is readily available from the aqueous sodium carbonate extra

SYNTHESIS OF dl-CORIOLIN

The total synthesis of dl-coriolin has been achieved in a stereoselective way.The key tricyclic intermediate was synthesized from dicyclopentadiene through a route which involved an SN2 reaction at a neopentylic position.

A NEW SYNTHESIS OF dl-CORIOLIN A. APPLICATION OF A NEW SN2 REACTION AT A NEOPENTYLIC POSITION

Dicyclopentadiene has been stereoselectively converted to a key tricyclic intermediate for the total synthesis of coriolin, through a route which involves a new SN2 reaction at a neopentylic position.