1272665-71-0

Basic information

• Product Name: N-methyl-N-(pyrimidin-2-yl)benzamide
• Synonyms: N-methyl-N-(pyrimidin-2-yl)benzamide
• CAS NO: 1272665-71-0
• Molecular Weight: 213.239
• Mol File: 1272665-71-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-methyl-N-(pyrimidin-2-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-N-(pyrimidin-2-yl)benzamide(1272665-71-0)
• EPA Substance Registry System: N-methyl-N-(pyrimidin-2-yl)benzamide(1272665-71-0)

Safety Data

• Hazardous Substances Data: 1272665-71-0(Hazardous Substances Data)

Upstream product

• 13053-89-9 N-(pyrimidin-2'-yl)benzamide 
• 74-88-4 methyl iodide 
• 931-61-3 N-methylpyrimidin-2-amine 
• 98-88-4 benzoyl chloride 
• 1722-12-9 2-chloropyrimidine 
• 88070-48-8 N-methylbenzamide 

Downstream Products

• 119-61-9 benzophenone 
• 134-84-9 4-Methylbenzophenone 
• 22679-54-5 4-tert-butylbenzophenone 
• 611-94-9 4-Methoxybenzophenone 
• 728-86-9 phenyl[4-(trifluoromethyl)phenyl]methanone 
• 131-58-8 2-Methylbenzophenone 
• 2553-04-0 ortho-methoxybenzophenone 
• 342-24-5 o-fluorobenzophenone 
• 53689-84-2 4-acetylbenzophenone 
• 6158-54-9 methyl 4-Benzoylbenzoate 
• 54225-86-4 (3,4-methylenedioxyphenyl) phenyl methanone 
• 6453-98-1 3-benzoylfuran 
• 6454-02-0 2-benzoylbenzo[b]thiophene 
• 84255-35-6 (6-methoxynaphthalen-2-yl)(phenyl)methanone 

Relevant articles and documents

N-Methylamino Pyrimidyl Amides (MAPA): Highly Reactive, Electronically-Activated Amides in Catalytic N-C(O) Cleavage

Despite recent progress in catalytic cross-coupling technologies, the direct activation of N-alkyl-N-aryl amides has been a challenging transformation. Here, we report the first Suzuki cross-coupling of N-methylamino pyrimidyl amides (MAPA) enabled by the controlled nN → πAr conjugation and the resulting remodeling of the partial double bond character of the amide bond. The new mode of amide activation is suitable for generating acyl-metal intermediates from unactivated primary and secondary amides.