Welcome to LookChem.com Sign In|Join Free

CAS

  • or

931-61-3

Post Buying Request

931-61-3 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

931-61-3 Usage

General Description

2-Pyrimidinamine, N-methyl- (9CI) is a chemical compound with the molecular formula C5H6N4. It is also known by its IUPAC name N-methylpyrimidin-2-amine. 2-Pyrimidinamine, N-methyl- (9CI) is a derivative of pyrimidine and belongs to the class of aminopyrimidines. It is a white, crystalline solid that is sparingly soluble in water. 2-Pyrimidinamine, N-methyl- (9CI) has several industrial and pharmaceutical applications, including its use as an intermediate in the synthesis of various pharmaceutical drugs and agricultural chemicals. It is important to handle this compound with care due to its potential hazardous properties.

Check Digit Verification of cas no

The CAS Registry Mumber 931-61-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,3 and 1 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 931-61:
(5*9)+(4*3)+(3*1)+(2*6)+(1*1)=73
73 % 10 = 3
So 931-61-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H7N3/c1-6-5-7-3-2-4-8-5/h2-4H,1H3,(H,6,7,8)

931-61-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name N-Methyl-2-pyrimidinamine

1.2 Other means of identification

Product number -
Other names N-methylpyrimidin-2-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:931-61-3 SDS

931-61-3Relevant articles and documents

Palladium-catalyzed remote C-H functionalization of 2-aminopyrimidines

Das, Animesh,Jana, Akash,Maji, Biplab

supporting information, p. 4284 - 4287 (2020/04/27)

A straightforward strategy was developed for the arylation and olefination at the C5-position of the N-(alkyl)pyrimidin-2-amine core with readily available aryl halides and alkenes, respectively. This approach was highly regioselective, and the transformation was achieved based on two different (Pd(ii)/Pd(iv)) and (Pd(0)/Pd(ii)) catalytic cycles.

N-Methylamino Pyrimidyl Amides (MAPA): Highly Reactive, Electronically-Activated Amides in Catalytic N-C(O) Cleavage

Meng, Guangrong,Lalancette, Roger,Szostak, Roman,Szostak, Michal

supporting information, p. 4656 - 4659 (2017/09/12)

Despite recent progress in catalytic cross-coupling technologies, the direct activation of N-alkyl-N-aryl amides has been a challenging transformation. Here, we report the first Suzuki cross-coupling of N-methylamino pyrimidyl amides (MAPA) enabled by the controlled nN → πAr conjugation and the resulting remodeling of the partial double bond character of the amide bond. The new mode of amide activation is suitable for generating acyl-metal intermediates from unactivated primary and secondary amides.

New 5-aryl-1H-imidazoles display in vitro antitumor activity against apoptosis-resistant cancer models, including melanomas, through mitochondrial targeting

Mathieu, Véronique,Van Den Berge, Emilie,Ceusters, Justine,Konopka, Tomasz,Cops, Antonin,Bruyère, Céline,Pirker, Christine,Berger, Walter,Trieu-Van, Tran,Serteyn, Didier,Kiss, Robert,Robiette, Rapha?l

, p. 6626 - 6637 (2013/10/01)

We designed and synthesized 48 aryl-1H-imidazole derivatives and investigated their in vitro growth inhibitory activity in cancer cell lines known to present various levels of resistance to proapoptotic stimuli. The IC50 in vitro growth inhibitory concentration of these compounds ranged from >100 μM to single digit μM. Among the most active compounds, 2i displayed similar in vitro growth inhibition in cancer cells independent of the cells' levels of resistance to proapoptotic stimuli and was found to be cytostatic in melanoma cell lines. Compound 2i was then tested by the National Cancer Institute Human Tumor Cell Line Anti-Cancer Drug Screen, and the NCI COMPARE algorithm did not reveal any correlation between its growth inhibition profiles with the NCI database compound profiles. The use of transcriptomically characterized melanoma models then enabled us to highlight mitochondrial targeting by 2i. This hypothesis was further confirmed by reactive oxygen production measurement and oxygen consumption analysis.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 931-61-3