127708-36-5Relevant academic research and scientific papers
FLUORO-2 PHENYL-2 AMINO-1 ETHANE: OBTENTION DES ENANTIOMERES, CONFIGURATION ABSOLUE ET EMPLOI COMME AGENT CHIRAL DE DERIVATION
Hamman, S.
, p. 377 - 388 (1989)
2-Fluoro-2-phenyl-1-aminoethane was synthesized from styrene.The enantiomers were separated and their absolute configurations were determined: the specific rotation of the amine with an R configuration is D20=-37.7 deg in methanol.This amine
Substituent effects in regio- And stereoselective ring-opening reaction of aziridines with ET3N·3HF for β-fluoroamine synthesis
Sasaki, Shigeru,Watanabe, Satono,Shiino, Kaori,Yanaka, Yuko,Kaneko, Shiho,Miyamoto, Kana,Yasui, Ayano,Sakaino, Hina,Teramoto, Hiroyoshi,Yamauchi, Takayasu,Higashiyama, Kimio
, p. 823 - 841 (2019/04/26)
This paper discusses the reactivity of various 2-substituted aziridine derivatives. The reaction of chiral 2-aryl-substituted aziridines with triethylamine trihydrofluoride (Et3N·3HF) afforded chiral E-fluoroamines with high stereoselectivity. In contrast
