127875-24-5

Upstream product

• 114079-11-7 2,2,2-trichloroethyl 4-O-acetyl-2,3,6-tri-O-benzyl-α-D-mannopyranoside 
• 24679-79-6 2,3,6-tri-O-benzyl-D-glucopyranoside 
• 19488-48-3 methyl O-2,3,6-tri-O-benzyl-α-D-glucopyranoside 
• 98-88-4 benzoyl chloride 
• 7177-79-9 methyl 2,3-di-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 3162-96-7 methyl 4,6-O-benzylidene-α-D-glucopyranoside 
• 61236-93-9 1,4-di-O-acetyl-2,3,6-tri-O-benzyl-D-glucopyranoside 
• 19488-48-3 methyl 2,3,6-tri-O-benzyl-D-glucopyranoside 
• 87908-32-5 2-methoxyethyl 2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 114219-41-9 2-methoxyethyl 2,3-di-O-benzyl-β-D-glucopyranoside 
• 100-44-7 benzyl chloride 
• 97974-20-4 (2R,3R,4S,5R,6S)-4,5-Bis-benzyloxy-2-benzyloxymethyl-6-phenylsulfanyl-tetrahydro-pyran-3-ol 
• 141263-03-8 ethyl 4-O-acetyl-2,3,6-tri-O-benzyl-1-thio-β-D-glucopyranoside 
• 89387-42-8 phenyl 4-O-acetyl-2,3,6-tri-O-benzyl-1-thio-β-D-glucopyranoside 

Downstream Products

• 114079-17-3 benzyl O-(4-O-acetyl-2,3,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 114079-16-2 benzyl O-(4-O-acetyl-2,3,6-tri-O-benzyl-β-D-mannopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 114079-15-1 4-O-acetyl-2,3,6-tri-O-benzyl-α-D-mannopyranosyl bromide 
• 736969-67-8 4-O-acetyl-2,3,6-tri-O-benzyl-α,β-D-glucopyranosyl trichloroimidate 
• 108811-18-3 1-O-benzyl-2-O-(2,3,6-tri-O-benzyl-α-D-glucopyranosyl)-3-deoxy-2(S)-glycerol 
• 108811-16-1 1-O-benzyl-2-O-(2,3,6-tri-O-benzyl-α-D-glucopyranosyl)-3-deoxy-2(R)-glycerol 
• 108811-13-8 2-O-benzyl-1-O-(2,3,6-tri-O-benzyl-α-D-glucopyranosyl)-3-deoxy-2(S)-glycerol 
• 89401-30-9 1-O-(4-O-acetyl-2,3,6-tri-O-benzyl-α-D-glucopyranosyl)-2-O-benzyl-3-deoxy-2(R)-glycerol 
• 89401-31-0 1-O-(4-O-acetyl-2,3,6-tri-O-benzyl-α-D-glucopyranosyl)-3-deoxy-2(S)-glycerol 
• 89387-41-7 phenyl-4-O-acetyl-2,3,6-tri-O-benzyl-1-deoxy-1-thio-D-glucopyranoside 
• 89387-47-3 1-O-benzyl-2-O-<4-O-<4-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl>-2,3,6-tri-O-benzyl-α-D-glucopyranosyl>-3-deoxy-2(S)-glycerol 

Relevant academic research and scientific papers

A useful and convenient synthetic procedure for hydrolysis of thioglycosides

Various thioglycosides 1 are smoothly hydrolyzed chemo-selectively to the corresponding 1-hydroxy sugars 2 in good yields at 0-5°C by employing (NH4)6Mo7O24· 4H2O-H2O2 or H2MoO4·H2O-H2O2 to promote oxidation of ammonium bromide in the presence of perchloric acid in CH2Cl2-H2O solvent system. Mild conditions, good yields, no side reactions such as bromination either at the anomeric position or double bond, and even oxidation at the sulfur are some of the major advantages.

Anti-coagulation pentasaccharide and preparing method and medical application thereof

The invention relates to a synthesized pentasaccharide compound, salt thereof, and application of the pentasaccharide compound in preparing medicines for preventing and/or treating blood coagulation disorder related diseases.

Anti-coagulation pentasaccharide and preparing method and medical application thereof

The invention relates to an anti-coagulation medicine, in particular to a synthesized pentasaccharide compound, salt thereof, and a preparing method and medical application of the pentasaccharide compound. The pentasaccharide compound or acid or salt thereof in the ion form shown in the formula III (the formula can be seen in the description) is synthesized and has stronger anti-coagulation factorXa activity and a longer elimination half life compared with sodium sulfonate. The pentasaccharide compound can be used for preparing medicines for preventing and treating blood coagulation disorderrelated diseases such as deep venous thrombosis, thrombophlebitis, artery blockage caused by thrombosis or embolism and postoperative vein thrombosis or embolism.

Anti-coagulation pentasaccharide compound and preparing method and medical application thereof

The invention relates to an anti-coagulation medicine, in particular to a synthesized pentasaccharide compound, salt thereof, and a preparing method and medical application of the pentasaccharide compound. The pentasaccharide compound or acid or salt thereof in the ion form shown in the formula II (the formula can be seen in the description) is synthesized and has stronger anti-coagulation factorXa activity and a longer elimination half life compared with sodium sulfonate. The pentasaccharide compound can be used for preparing medicines for preventing and treating blood coagulation disorder related diseases such as deep venous thrombosis, thrombophlebitis, artery blockage caused by thrombosis or embolism and postoperative vein thrombosis or embolism.

A Mild and Environmentally Benign Synthetic Protocol for Catalytic Hydrolysis of Thioglycosides

A wide variety of thioglycosides 1 are selectively hydrolyzed to the corresponding 1-hydroxy sugars 2 in good yields at 0-5 deg C, by employing V2O5-H2O2 catalyzed oxidation of ammonium bromide in CH2Cl2-H2O solvent system. The methodology is very mild, environmentally benign, efficient and highly chemoselective. No side reactions such as bromination either at the anomeric position or double bond or oxidation at the sulfur are encountered.

Chemical synthesis of 6'''-α-maltotriosyl-maltohexaose as substrate for enzymes in starch biosynthesis and degradation

A branched nonasaccharide 6'''-α-maltotriosyl-maltohexaose was synthesised in 40 steps from D-glucose and maltose. Phenyl O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-(1→4)-O-(2,3,6-tri-O-benzyl-α-D-glucopyranosyl)-(1→4)-2,3-di-O-benzyl-1-thio-β-D-glucop

Stereoselective total synthesis of wheat flour ceramide dihexoside.

A plant glycosphingolipid, O-(beta-D-mannopyranosyl)-(1----4)-O-(beta-D-glucopyranosyl)-(1----1)-(2 S,3S,4R)-4-hydroxy-N-tetracosanoylsphinganine 1, and the stereoisomer, O-(alpha-D-mannopyranosyl)-(1----4)-O-(beta-d-glucopyranosyl)-(1----1)-( 2S,3S,4R)-4

A NOVEL PROCEDURE FOR THE PREPARATION OF 1-OH SUGAR DERIVATIVES USING 2-METHOXYETHYL GLYCOSIDES

Treatment of benzyl-protected 2-methoxyethyl glycopyranosides with titanium tetrachloride followed by hydrolysis provides a new method for the preparation of the corresponding 1-OH sugar derivatives.The present method is shown to be useful for the prepara