1280206-29-2

Upstream product

• 16532-79-9 4-Bromophenylacetonitrile 
• 124276-67-1 1-(4-bromophenyl)cyclopropanecarbonitrile 
• 345965-52-8 1-(4-bromophenyl)cyclopropanecarboxylic acid 
• 1215205-50-7 ethyl 1-(4-bromophenyl)cyclopropane-1-carboxylate 
• 1257213-52-7 1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropane-1-carboxylic acid ethyl ester 
• 1280206-27-0 1-[4'-(4-hydroxymethyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester 
• 1280205-98-2 (5-(4-bromophenyl)-3-methylisoxazole-4-yl)methanol 
• 1228689-61-9 methyl 5-(4-bromophenyl)-3-methylisoxazole-4-carboxylate 
• 85963-90-2 methyl 2-(4-bromobenzoyl)-3-oxo-butanoate 

Downstream Products

• 1280206-28-1 1-[4'-(3-Methyl-4-phenethyloxymethyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid 
• 1280206-32-7 1-[4'-(3-methyl-4-phenethylsulfanylmethyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester 
• 1280732-31-1 1-{4'-[3-methyl-4-(3-phenylpyrazol-1-ylmethyl)isoxazol-5-yl]biphenyl-4-yl}cyclopropanecarboxylic acid 
• 1280732-40-2 1-[4'-(4-azidomethyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester 
• 1280732-41-3 1-{4'-[4-(4-Benzyl-[1,2,3]triazol-1-ylmethyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester 
• 1280206-31-6 1-[4'-(3-Methyl-4-phenethylsulfanylmethyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid 
• 1280208-32-3 N-[1-[4'-(3-Methyl-4-phenethylsulfanylmethyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarbonyl]-methanesulfonamide 

Relevant academic research and scientific papers

POLYCYCLIC COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS

Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.

Compounds as Lysophosphatidic Acid Receptor Antagonists

Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in com