128080-52-4Relevant academic research and scientific papers
Copper-Catalyzed Unstrained C-C Single Bond Cleavage of Acyclic Oxime Acetates Using Air: An Internal Oxidant-Triggered Strategy toward Nitriles and Ketones
Zhu, Chuanle,Chen, Fulin,Liu, Chi,Zeng, Hao,Yang, Zhiyi,Wu, Wanqing,Jiang, Huanfeng
, p. 14713 - 14722 (2018/12/14)
A copper-catalyzed aerobic oxidative C-C single bond cleavage of acyclic unstrained oxime acetates is reported, providing various aryl nitriles and ketones in good yields. Mechanistic studies indicate a radical procedure is involved in this transformation, and the oxygen atom in the ketone products is originated from O2 in the air. Oxime acetates as an internal oxidant have been proved to be an initiator, which may promote the discovery of novel protocol for C-C bond cleavage and dioxygen activation.
Divergent Iron-Catalyzed Coupling of O-Acyloximes with Silyl Enol Ethers
Yang, Hai-Bin,Selander, Nicklas
supporting information, p. 1779 - 1783 (2017/02/15)
An iron-catalyzed coupling reaction of O-acyloximes and O-benzoyl amidoximes with silyl enol ethers is reported. The protocol provides access to functionalized pyrroles, 1,6-ketonitriles, pyrrolines and imidazolines via carbon-centered radicals generated from an initially formed iminyl radical. The intramolecular cyclization and ring-opening processes of the iminyl radical take place preferentially over reactions that proceed through a 1,3-hydrogen transfer, providing insights into iron-catalyzed reactions with oxime derivatives. The cheap and environmentally friendly iron catalyst, the broad substrate scope and the functional group compatibility make this protocol useful for synthesis of valuable nitrogen-containing products.
BENZOPHENANTHRIDINES. X. INVESTIGATION OF THE RODIONOV-SUVOROV SCHEME. REDUCTIVE ACETYLATION OF THE OXIMES OF 3-ETHOXYCARBONYL-SUBSTITUTED 2-PHENYLTETRAL-1-ONES WITH STANNOUS CHLORIDE IN ACETIC ANHYDRIDE
Maslennikova, L. V.,Sladkov, V. I.,Levina, I. I.,Kurkovskaya, L. N.,Suvorov, N. N.
, p. 2165 - 2170 (2007/10/02)
When treated with anhydrous stannous chloride in acetic anhydride, the oximes of benzyl phenyl ketone and 3-alkoxycarbonyl- and 3,3-dialkoxycarbonyl-2-phenyltetralones give a mixture of enamides and enimides.The direction of the reaction does not depend on the configuration of the oxime.It takes place in a more well-defined manner with the derivatives of 2-phenyltetralones used in the synthesis of benzophenanthridines by the Rodionov-Suvorov method.
