128134-36-1

Upstream product

• 98-86-2 acetophenone 
• 104-87-0 4-methyl-benzaldehyde 
• 22252-14-8 (E)-3-(4-methylphenyl)-1-phenyl-2-propen-1-one 
• 4224-87-7 4-methyl-chalcone 
• 70-11-1 α-bromoacetophenone 
• 622-97-9 1-ethenyl-4-methylbenzene 
• 100-52-7 benzaldehyde 
• 532-27-4 1-chloroacetophenone 
• 4636-16-2 iodoacetophenone 
• 100-42-5 styrene 

Downstream Products

• 67295-29-8 2-hydroxy-3-morpholin-4-yl-1-phenyl-3-p-tolyl-propan-1-one 
• 371961-32-9 2-Hydroxy-3-methoxy-1-phenyl-3-p-tolyl-propan-1-one 
• 33951-38-1 p-Methylbenzyl-phenylglycolsaeure 
• 766-76-7 benzoate 
• 71-47-6 formate 
• 104-87-0 4-methyl-benzaldehyde 
• 54458-33-2 1-phenyl-3-(p-tolyl)propane-1,2,3-trione 
• 2431-00-7 p-methylbenzil 
• 189017-48-9 (2R,3S)-epoxy-3-(4-methylphenyl)-1-phenylpropan-1-one 
• 93633-29-5 3-Oxo-3-phenyl-2-p-tolyl-propionaldehyde 
• 28384-49-8 1-phenyl-2-(p-tolyl)prop-2-en-1-one 
• 1430342-23-6 2-(4-methylphenyl)-3-hydroxy-1-phenylpropan-1-one 

Relevant academic research and scientific papers

Superactive Mg-Al-O-t-Bu hydrotalcite for epoxidation of olefins

Epoxidation of unfunctionalised olefins and α,β-unsaturated ketones has been accomplished at an amazingly and unprecedented rate by superactive Mg-Al-O-t-Bu-hydrotalcite solid base catalyst prepared in our laboratory.

Enantioselective epoxidation of olefins with H2O2 catalyzed by bioinspired aminopyridine manganese complexes

A novel family of bioinspired manganese(II) complexes bearing chiral aminopyridine ligands that possessed additional aromatic groups and strong donating dimethylamino groups were synthesized and characterized. These manganese complexes exhibited efficient

Asymmetric Epoxidation of α,β-Unsaturated Ketones Catalyzed by Chiral Polybinaphthyl Zinc Complexes: Greatly Enhanced Enantioselectivity by a Cooperation of the Catalytic Sites in a Polymer Chain

Polybinaphthyl zinc catalysts have been developed for the asymmetric epoxidation of a,/3-unsaturated ketones in the presence of tert-butyl hydroperoxide. Up to 81% ee has been achieved for the epoxidation of α,β-unsaturated ketones containing β-aliphatic

Highly selective multifunctional nanohybrid catalysts for the one-pot synthesis of α,β-epoxy-chalcones

An efficient one-pot heterogeneous process for producing chiral α,β-epoxy-chalcones from the corresponding aldehydes and ketones has been described. The nanohybrid materials based on poly-l-leucine immobilised into rehydrated hydrotalcites did not require any pre-activation and were easily recovered and recycled for four consecutive runs without losing their catalytic efficiency in terms of conversion, total selectivity towards the corresponding epoxy-chalcones and excellent enantioselectivity.

Phase-transfer catalyzed asymmetric epoxidation of chalcones using chiral crown ethers derived from D-glucose, D-galactose, and D-mannitol

Chiral monoaza-15-crown-5 lariat ethers synthesized from D-glucose, D-galactose, and D-mannitol have been applied as phase-transfer catalysts in the enantioselective epoxidation of chalcones with tert-butylhydroperoxide. The type of monosaccharide on the

Asymmetric Cascade Catalysis with Chiral Polyoxometalate-Based Frameworks: Sequential Direct Aldol and Epoxidation Reactions

Catalytic asymmetric cascade reactions in which the substrates are transferred through well-choreographed consecutive independent steps by a single catalyst have received increasing interest. By incorporating a chiral organocatalyst pyrrolidine, an oxidat

Diaryl-2-pyrrolidinemethanols catalyzed enantioselective epoxidation of α,β-enones: new insight into the effect of structural modification of the catalyst on reaction efficiency

Catalytic enantioselective epoxidation of α,β-unsaturated ketones promoted by diaryl-2-pyrrolidinemethanols and tert-butyl hydroperoxide (TBHP) is described. Investigation on structural modifications of the diaryl-2-pyrrolidinemethanols showed that fine t

Highly catalytic enantioselective epoxidation of enones with weak base bicarbonate and hydrogen peroxide

The weak basic bicarbonate-activated hydrogen peroxide is applied to the catalytic asymmetric epoxidation of the enones, and the catalyst polyleucine cannot be deteriorated and can successfully be reused in this asymmetric reaction. The ee value of the op

Highly Enantioselective Epoxidation of α,β-Unsaturated Ketones Using Amide-Based Cinchona Alkaloids as Hybrid Phase-Transfer Catalysts

A series of 20 one chiral epoxides were obtained with excellent yields (up to 99%) and enantioselectivities (up to >99% ee) using hybrid amide-based Cinchona alkaloids. Our method is characterized by low catalyst loading (0.5 mol %) and short reaction times. Moreover, the epoxidation process can be carried out in 10 cycles, without further catalyst addition to the reaction mixture. This methodology significantly enhance the scale of the process using very low catalyst loading.

Organocatalytic Enantioselective γ-Elimination: Applications in the Preparation of Chiral Peroxides and Epoxides

An organocatalyzed enantioselective γ-elimination process has been achieved and applied in the kinetic resolution of peroxides to access chiral peroxides and epoxides. The reaction provided a pathway for the preparation of two useful synthetic and biologically important structural motifs through a single-step reaction. A range of substrates has been resolved with a selectivity factor up to 63. The obtained enantioenriched peroxides and epoxides allowed a series of transformations with retained optical purities.