128271-37-4

Basic information

• Product Name: (3-Chloro-phenyl)-(3-phenylsulfanylmethyl-pyridin-2-yl)-amine
• CAS NO: 128271-37-4
• Molecular Weight: 326.849
• Mol File: 128271-37-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3-Chloro-phenyl)-(3-phenylsulfanylmethyl-pyridin-2-yl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (3-Chloro-phenyl)-(3-phenylsulfanylmethyl-pyridin-2-yl)-amine(128271-37-4)
• EPA Substance Registry System: (3-Chloro-phenyl)-(3-phenylsulfanylmethyl-pyridin-2-yl)-amine(128271-37-4)

Safety Data

• Hazardous Substances Data: 128271-37-4(Hazardous Substances Data)

Upstream product

• 2942-59-8 2-chloronicotinic acid 
• 108-42-9 3-chloro-aniline 
• 57978-41-3 2-<(3-chlorophenyl)amino>-3-pyridinecarboxylic acid 
• 59272-28-5 2-(3-Chlorophenyl)amino-3-hydroxymethylpyridine 
• 108-98-5 thiophenol 

Downstream Products

• 127555-61-7 1,3-dihydro-1-(3-chlorophenyl)-3-(phenylthio)-2H-pyrrolo[2,3-b]pyridin-2-one 
• 127555-27-5 1-(3-chlorophenyl)-1,3-dihydro-3,3-dimethyl-2H-pyrrolo[2,3-b]pyridin-2-one 

Relevant articles and documents

Substituted 1,3-Dihydro-2H-pyrrolopyridin-2-ones as Potential Antiinflammatory Agents

A series of analogues based on the 1,3-dihydro-2H-pyrrolopyridin-2-one ring system have been synthesized and shown to possess oral antiinflammatory activity in both the reverse passive Arthus reaction (RPAR) pleural cavity assay in rats and in the adjuvant-induced arthritic rat model (AAR).Several members of this series additionally exhibit an inhibitory effect on the in vivo production of prostaglandin- and leukotriene-derived products or arachidonic acid metabolism although these compounds exhibit no significant inhibitory activity against the cyclooxygenase and 5-lipoxygenase enzymes in vitro.Structure-activity relationships in this series are discussed.