59272-28-5

Basic information

• Product Name: 2-(3-Chlorophenyl)amino-3-hydroxymethylpyridine
• CAS NO: 59272-28-5
• Molecular Weight: 234.685
• Mol File: 59272-28-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(3-Chlorophenyl)amino-3-hydroxymethylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-Chlorophenyl)amino-3-hydroxymethylpyridine(59272-28-5)
• EPA Substance Registry System: 2-(3-Chlorophenyl)amino-3-hydroxymethylpyridine(59272-28-5)

Safety Data

• Hazardous Substances Data: 59272-28-5(Hazardous Substances Data)

Upstream product

• 108-42-9 3-chloro-aniline 
• 2942-59-8 2-chloronicotinic acid 
• 57978-41-3 2-<(3-chlorophenyl)amino>-3-pyridinecarboxylic acid 

Downstream Products

• 127555-61-7 1,3-dihydro-1-(3-chlorophenyl)-3-(phenylthio)-2H-pyrrolo[2,3-b]pyridin-2-one 
• 128271-37-4 (3-Chloro-phenyl)-(3-phenylsulfanylmethyl-pyridin-2-yl)-amine 
• 127555-27-5 1-(3-chlorophenyl)-1,3-dihydro-3,3-dimethyl-2H-pyrrolo[2,3-b]pyridin-2-one 

Relevant articles and documents

Substituted 1,3-Dihydro-2H-pyrrolopyridin-2-ones as Potential Antiinflammatory Agents

A series of analogues based on the 1,3-dihydro-2H-pyrrolopyridin-2-one ring system have been synthesized and shown to possess oral antiinflammatory activity in both the reverse passive Arthus reaction (RPAR) pleural cavity assay in rats and in the adjuvant-induced arthritic rat model (AAR).Several members of this series additionally exhibit an inhibitory effect on the in vivo production of prostaglandin- and leukotriene-derived products or arachidonic acid metabolism although these compounds exhibit no significant inhibitory activity against the cyclooxygenase and 5-lipoxygenase enzymes in vitro.Structure-activity relationships in this series are discussed.