59272-28-5

Upstream product

• 108-42-9 3-chloro-aniline 
• 2942-59-8 2-chloronicotinic acid 
• 57978-41-3 2-<(3-chlorophenyl)amino>-3-pyridinecarboxylic acid 

Downstream Products

• 127555-61-7 1,3-dihydro-1-(3-chlorophenyl)-3-(phenylthio)-2H-pyrrolo[2,3-b]pyridin-2-one 
• 128271-37-4 (3-Chloro-phenyl)-(3-phenylsulfanylmethyl-pyridin-2-yl)-amine 
• 127555-27-5 1-(3-chlorophenyl)-1,3-dihydro-3,3-dimethyl-2H-pyrrolo[2,3-b]pyridin-2-one 

Relevant academic research and scientific papers

Substituted 1,3-Dihydro-2H-pyrrolopyridin-2-ones as Potential Antiinflammatory Agents

A series of analogues based on the 1,3-dihydro-2H-pyrrolopyridin-2-one ring system have been synthesized and shown to possess oral antiinflammatory activity in both the reverse passive Arthus reaction (RPAR) pleural cavity assay in rats and in the adjuvant-induced arthritic rat model (AAR).Several members of this series additionally exhibit an inhibitory effect on the in vivo production of prostaglandin- and leukotriene-derived products or arachidonic acid metabolism although these compounds exhibit no significant inhibitory activity against the cyclooxygenase and 5-lipoxygenase enzymes in vitro.Structure-activity relationships in this series are discussed.

Phenylnaphthyridines containing a methyl substituent in the 3-position useful in the treatment of ulcers

The present invention relates to the compounds corresponding to the formula: STR1 in which: X, Y and Z are selected from the following combinations: (a) Y=Z=H and X is m-CH3, m,p-Cl, m-SCH3, m,o,p-F, m,p-CN,CONH2, m-CHsub