128779-65-7Relevant academic research and scientific papers
Chemical combination of 6-deoxy-6-mycoloylamino-α,α-trehalose and N-acetyl-6-O-(aminoacyl)muramoyl dipeptide
Ishida, Hideharu,Ogawa, Yuji,Imai, Yasuyuki,Kiso, Makoto,Hasegawa, Akira,Sakurai, Takuma,Azuma, Ichiro
, p. 199 - 208 (1989)
6-Deoxy-6-mycoloylamino-α,α-trehalose, a biologically active derivative of 6,6′-di-O-mycoloyl-α,α-trehalose (TDM), and N-acetyl-6-O-(aminoacyl)-muramoyl dipeptide (MDP) were joined chemically by a succinic acid unit. The compounds synthesized showed activ
Convergent synthesis of novel muramyl dipeptide analogues: Inhibition of porphyromonas gingivalis-induced pro-inflammatory effects by high doses of muramyl dipeptide
Cai, Bin,Panek, James S.,Amar, Salomon
, p. 6878 - 6890 (2016/08/05)
Porphyromonas gingivalis (P.g.)-induced TNF-α can be affected by muramyl dipeptide (MDP) in a biphasic concentration-dependent manner. We found that in P.g.-exposed macrophages, treatment with 10 μg/mL of MDP (MDP-low) up-regulated TNF-α by 29%, while 100
