19522-39-5

Basic information

• Product Name: Nsc92153
• Synonyms: Nsc92153;D-4-(CarboxyaMino)-glutaraMic Acid 4-Benzyl Ester;(4R)-5-AMino-5-oxo-4-[[(phenylMethoxy)carbonyl]aMino]-pentanoic Acid;(R)-5-AMino-5-oxo-4-[[(phenylMethoxy)carbonyl]aMino]-pentanoic Acid
• CAS NO: 19522-39-5
• Molecular Formula: C₁₃H₁₆N₂O₅
• Molecular Weight: 280.27654
• Product Categories: Amino Acids & Derivatives;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Amino Acids & Derivatives, Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 19522-39-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 589.8°Cat760mmHg
• Flash Point: 310.5°C
• Appearance: /
• Density: 1.316g/cm³
• Storage Temp.: Refrigerator
• Solubility: Methanol
• CAS DataBase Reference: Nsc92153(CAS DataBase Reference)
• NIST Chemistry Reference: Nsc92153(19522-39-5)
• EPA Substance Registry System: Nsc92153(19522-39-5)

Safety Data

• Hazardous Substances Data: 19522-39-5(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

Nsc92153 is used in the synthesis of Cbz-aminoglutarimides and Cbz-succinimides, for their anticonvulsant activity.

Upstream product

• 71869-80-2 benzyl (R)-(2,6-dioxotetrahydro-2H-pyran-3-yl)carbamate 
• 501-53-1 benzyl chloroformate 
• 6893-26-1 D-Glutamic acid 
• 63648-73-7 N-benzyloxycarbonyl-D-glutamic acid 

Downstream Products

• 19522-40-8 D-α-glutamine 
• 129145-09-1 ((R)-1-Carbamoyl-3-dibutylcarbamoyl-propyl)-carbamic acid benzyl ester 
• 77340-94-4 tert-butyl (4R)-4-(benzyloxycarbonylamino)-4-carbamoylbutyrate 
• 367276-23-1 Cbz-D-iso-Gln(NHS) 
• 55297-72-8 (R)-5-amino-4-((tert-butoxycarbonyl)amino)-5-oxopentanoic acid 
• 18814-49-8 tert-butoxycarbonyl-L-alanyl-D-isoglutamine benzyl ester 
• 66025-93-2 (S)-1-(((R)-1-amino-5-(benzyloxy)-1,5-dioxopentan-2-yl)amino)-1-oxopropan-2-aminium 2,2,2-trifluoroacetate 
• 69323-69-9 benzyl (R)-4-((S)-2-((R)-2-(((4aR,6S,7R,8R,8aS)-7-acetamido-6-(benzyloxy)-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-8-yl)oxy)propanamido)propanamido)-5-amino-5-oxopentanoate 
• 62928-83-0 benzyl (R)-4-((S)-2-((R)-2-(((2S,3R,4R,5S,6R)-3-acetamido-2-(benzyloxy)-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)propanamido)propanamido)-5-amino-5-oxopentanoate 
• 108607-04-1 N-benzyloxycarbonyl-L-alanyl-D-isoglutamine tert-butyl ester 
• 367276-24-2 (R)-2-{(R)-2-[(S)-2-((R)-4-Benzyloxycarbonylamino-4-carbamoyl-butyrylamino)-6-(2,2,2-trifluoro-acetylamino)-hexanoylamino]-propionylamino}-propionic acid methyl ester 
• 292150-20-0 N-Fmoc-D-isoglutamine 
• 129145-06-8 ((R)-3-Butylcarbamoyl-1-carbamoyl-propyl)-carbamic acid benzyl ester 
• 129145-10-4 6-((R)-4-Benzyloxycarbonylamino-4-carbamoyl-butyrylamino)-2-tert-butoxycarbonylamino-hexanoic acid methyl ester 

Relevant articles and documents

A novel immunostimulator, N2-[α-O-Benzyl-N-(acetylmuramyl) -L-alanyl-D-isoglutaminyl]-N6-trans-(m-nitrocinnamoyl)-L-lysine, and its adjuvancy on the hepatitis B surface antigen

N2-[α-O-Benzyl-N-(acetylmuramyl)-L-alanyl-D-isoglutaminyl] -N6-trans-(m-nitrocinnamoyl)-L-lysine (muramyl dipeptide C, or MDP-C) has been synthesized as a novel, nonspecific immunomodulator. The present study shows that MDP-C induces

Convergent synthesis of novel muramyl dipeptide analogues: Inhibition of porphyromonas gingivalis-induced pro-inflammatory effects by high doses of muramyl dipeptide

Porphyromonas gingivalis (P.g.)-induced TNF-α can be affected by muramyl dipeptide (MDP) in a biphasic concentration-dependent manner. We found that in P.g.-exposed macrophages, treatment with 10 μg/mL of MDP (MDP-low) up-regulated TNF-α by 29%, while 100