1289207-31-3

Upstream product

• 25808-30-4 2-(methylamino)acetonitrile hydrochloride 
• 34884-10-1 1-methyl-1H-pyrrole-2-carbonitrile 
• 1289207-30-2 4-bromo-1-methyl-1H-pyrrole-2-carbonitrile 
• 5720-07-0 4-methoxyphenylboronic acid 

Downstream Products

• 1289206-26-3 5-bromo-3-(2,4-dimethylfuran-3-yl)-N'-hydroxy-4-(4-hydroxyphenyl)-1-methyl-1H-pyrrole-2-carboximidamide 
• 1289207-32-4 5-bromo-4-(4-methoxyphenyl)-1-methyl-1H-pyrrole-2-carbonitrile 
• 1289207-33-5 5-bromo-3-iodo-4-(4-methoxyphenyl)-1-methyl-1H-pyrrole-2-carbonitrile 
• 1289207-35-7 5-bromo-4-(4-hydroxyphenyl)-3-iodo-1-methyl-1H-pyrrole-2-carbonitrile 
• 1289207-36-8 5-bromo-3-(2,4-dimethylfuran-3-yl)-4-(4-hydroxyphenyl)-1-methyl-1H-pyrrole-2-carbonitrile 

Relevant academic research and scientific papers

The application of vinamidinium salts to the synthesis of 1,2,4-trisubstituted pyrroles

The synthesis of 1-methyl-2-cyano-4-arylsubstituted pyrroles by the condensation of symmetrical vinamidinium salts with methyl aminoacetonitrile has been accomplished for the first time. Simple experimental conditions were used to prepare seven different

SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS

The invention provides a compound of formula (I) wherein G is a pyrrole or imidazole moiety and R4, R5, R6, R7 are as defined in the specification; or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity.