129141-66-8Relevant articles and documents
A synthesis of 5'-O-acryloyl-5-fluorouridine by use of p-methoxybenzyl group as an N3-imide protecting group of 5-fluorouridine
Akiyama,Takesue,Kumegawa,Nishimoto,Ozaki
, p. 2266 - 2269 (2007/10/02)
5'-O-Acryloyl-5-fluorouridine was preparedd by use of p-methoxybenzyl (PMB) group as an N3-imide protecting group of 5-fluorouridine. PMB group was introduced chemoselectively by use of N,N-diisopropylethylamine or DBU as a base. A new deprotection method was developed by means of AlCl3-anisole system at room temperature.