129354-36-5

Basic information

• Product Name: 2-amino-4-(4-methoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
• Synonyms: 2-amino-4-(4-methoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
• CAS NO: 129354-36-5
• Molecular Formula: C₁₉H₂₀N₂O₃
• Molecular Weight: 324.3737
• Mol File: 129354-36-5.mol
• Article Data: 124

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-amino-4-(4-methoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-(4-methoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile(129354-36-5)
• EPA Substance Registry System: 2-amino-4-(4-methoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile(129354-36-5)

Safety Data

• Hazardous Substances Data: 129354-36-5(Hazardous Substances Data)

Usage

Main properties

Chemical compound
Potential biological properties
Synthetic derivative of oligomycin A
Potential use in cancer therapy
Ability to disrupt cellular respiration
Ability to induce apoptosis in cancer cells
Potential as an antibacterial and antifungal agent

Also known as

Dimethyloligomycin A

Derived from

Oligomycin A

Mechanism of action

inhibition of ATP synthase enzyme in mitochondria

Potential applications

cancer therapy, antibacterial agent, antifungal agent

Need for further research

to fully understand therapeutic applications and mechanisms of action

Upstream product

• 3471-13-4 dimedone 
• 123-11-5 4-methoxy-benzaldehyde 
• 109-77-3 malononitrile 
• 675-10-5 4-hydroxy-6-methyl-2-pyron 
• 126-81-8 dimedone 
• 2826-26-8 2-(4-methoxyphenylmethylene)malononitrile 

Downstream Products

• 1229931-89-8 2-(4-chlorophenylamino)-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7,7-dimethyl-5-oxoquinoline-3-carbonitrile 
• 1229931-83-2 4-(4-methoxyphenyl)-5,6,7,8-tetrahydro-7,7-dimethyl-5-oxo-2-(phenylamino)quinoline-3-carbonitrile 
• 1229932-02-8 2-(cyclohexylamino)-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7,7-dimethyl-5-oxoquinoline-3-carbonitrile 
• 1610831-47-4 ethyl 2-cyano-3-(4-methoxyphenyl)-6,6-dimethyl-4-oxo-2,3,4,5,6,7-hexahydrobenzofuran-2-carboxylate 
• 1610831-50-9 2-cyano-3-(4-methoxyphenyl)-6,6-dimethyl-4-oxo-2,3,4,5,6,7-hexahydrobenzofuran-2-carboxamide 
• 1394250-80-6 4-(4-methoxy-phenyl)-7,7-dimethyl-2,5-dioxo-1,2,3,4,5,6,7,8-octahydro-quinoline-3-carbonitrile 
• 761357-05-5 4-(2,4-dichlorophenyl)-6-oxo-2-phenyl-1,6-dihydro-5-pyrimidinecarbonitrile 

Relevant articles and documents

Synthesis of some new chromeno[2,3-b]pyridine and [1,2,4]Triazolo[1,5-a]quinoline nucleoside analogues with expected biological activity

Direct preparation of 2-amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7,7-dimethyl-5-oxo-4H-chromene-3- carbonitrile (2) and 1,2-diamino-1,4,5,6,7,8-hexahydro-4-(4-methoxyphenyl)-7,7-dimethyl-5-oxo-3-quinolinecarbonitrile (11) which were utilized as starti

Synthesis and antimicrobial activities of new S-nucleosides of chromeno[2,3-B[pyridine derivatives and C-nucleosides of [1,2,4]Triazolo[1,5- A[quinoline derivatives

Direct preparation of 2-amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7,7- dimethyl-5-oxo-4H-chromene-3-carbonitrile 2 and 1,2-diamino-1,4,5,6,7,8- hexahydro-4-(4-methoxyphenyl)-7,7-dimethyl-5-oxo-3-quinolinecarbonitrile 11, which were utilized as starting

Solvent Selective Polyacrylonitrile Fiber as a Recyclable Catalyst for the Knoevenagel-Michael Reaction in Water

Heterogeneous catalysis is an important branch of sustainable chemistry. In this work, a series of polyacrylonitrile fiber (PANF) fiber catalysts (PANF-E, PANF-EDs, and PANF-D) with different catalytic micro-environments are developed and characterized by

Composite of magnetic carbon quantum dot-supported ionic liquid and Cu-BDC (CCDC no. 687690) MOF: A triple catalytic composite for chemical transformations

A novel magnetic triple composite was synthesized through immobilization of DABCO-based ionic liquid on magnetic carbon quantum dot, followed by conjugation of the resultant compound with a copper-based metal-organic framework (CCDC no. 687690). The as-pr

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