129371-91-1

Basic information

• Product Name: (R)-(-)-2-(3,3-dimethylbutyro-1,4-lactonyl) Z-3-phenyl-4-phthalimidobut-2-enoate
• Synonyms: (R)-(-)-2-(3,3-dimethylbutyro-1,4-lactonyl) Z-3-phenyl-4-phthalimidobut-2-enoate
• CAS NO: 129371-91-1
• Molecular Weight: 419.434
• Mol File: 129371-91-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-(-)-2-(3,3-dimethylbutyro-1,4-lactonyl) Z-3-phenyl-4-phthalimidobut-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-2-(3,3-dimethylbutyro-1,4-lactonyl) Z-3-phenyl-4-phthalimidobut-2-enoate(129371-91-1)
• EPA Substance Registry System: (R)-(-)-2-(3,3-dimethylbutyro-1,4-lactonyl) Z-3-phenyl-4-phthalimidobut-2-enoate(129371-91-1)

Safety Data

• Hazardous Substances Data: 129371-91-1(Hazardous Substances Data)

Upstream product

• 599-04-2 (R)-Pantolacton 
• 129371-89-7 (R)-(-)-2-(3,3-dimethylbutyro-1,4-lactonyl) E-3-phenylbut-2-enoate 
• 704-80-3 (E)-3-phenyl-2-butenoic acid 
• 129371-90-0 (R)-(-)-2-(3,3-dimethylbutyro-1,4-lactonyl) Z-4-bromo-3-phenylbut-2-enoate 
• 1074-82-4 potassium phtalimide 

Downstream Products

• 1078-21-3 (S)-Phenibut 
• 1078-21-3 (R)-Phenibut 
• 129371-93-3 (S)-4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-butyric acid (R)-4,4-dimethyl-2-oxo-tetrahydro-furan-3-yl ester 
• 129371-92-2 (R)-4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-butyric acid (R)-4,4-dimethyl-2-oxo-tetrahydro-furan-3-yl ester 

Relevant articles and documents

A NEW SYNTHESIS, RESOLUTION AND IN VITRO ACTIVITIES OF (R)- AND (S)-β-PHENYL-GABA

β-Phenyl-GABA (2) was resolved by separation by crystallization and/or h.p.l.c. of the diastereoisomeric (R)-(-)-pantolactone esters of the N-phthalimido protected β-phenyl-GABA.The absolute stereochemical assignments obtained from chiroptical studies of the enantiomers (8a) and (8b) and an X-ray crystallographic study of the diastereoisomer (7a) were supported by the activities of the enantiomers (8a) and (8b) in binding and electrophysiological studies.Details of synthesis, binding, electrophysiological, chiroptical and X-ray crystallographic studies are reported.