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129644-24-2

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129644-24-2 Usage

General Description

1-[4-(2-chloro-phenoxy)-phenyl]-ethanone is a chemical compound with the molecular formula C14H11ClO2. It is a ketone derivative with a molecular weight of 248.69 g/mol. 1-[4-(2-CHLORO-PHENOXY)-PHENYL]-ETHANONE contains a phenyl ring substituted with a 2-chloro-phenoxy group and a ketone group. It is used as an intermediate in the synthesis of pharmaceuticals and organic compounds, and it may also have potential applications in the field of materials science. The 2-chloro-phenoxy group contributes to the compound's hydrophobic properties, and its structure makes it suitable for various chemical reactions and modifications. More research is needed to fully understand its potential uses and properties.

Check Digit Verification of cas no

The CAS Registry Mumber 129644-24-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,6,4 and 4 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 129644-24:
(8*1)+(7*2)+(6*9)+(5*6)+(4*4)+(3*4)+(2*2)+(1*4)=142
142 % 10 = 2
So 129644-24-2 is a valid CAS Registry Number.

129644-24-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[4-(2-Chlorophenoxy)phenyl]ethanone

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:129644-24-2 SDS

129644-24-2Downstream Products

129644-24-2Relevant articles and documents

With substituted pyrazine and imidazole derivatives, their preparation and their use in medicine (by machine translation)

-

Paragraph 0157; 0159; 0160; 0161; 0162, (2017/10/12)

The invention discloses a substituted pyrazine and imidazole derivatives, their preparation and their use in medicine. Specifically, the invention relates to a compound of general formula (I) indicated by the new derivative and its pharmaceutically acceptable salt or pharmaceutical composition containing the same, and its preparation method. The invention also discloses the derivative and its pharmaceutically acceptable salt or pharmaceutical composition containing the same in the Bruton tyrosine kinase inhibitors, and in preparing and treating and/or preventing tumor diseases such as inflammation of the application of the medicament. Wherein the general formula (I) of each substituent as defined in the specification. (by machine translation)

Synthesis and evaluation of substituted 4-aryloxy- and 4-arylsulfanyl- phenyl-2-aminothiazoles as inhibitors of human breast cancer cell proliferation

Gorczynski, Michael J.,Leal, Rachel M.,Mooberry, Susan L.,Bushweller, John H.,Brown, Milton L.

, p. 1029 - 1036 (2007/10/03)

Several substituted 4-aryloxy- and 4-arylsulfanyl-phenyl-2-aminothiazoles were synthesized and evaluated for cytotoxic activity against estrogen-positive, estrogen-negative, and adriamycin-resistant human breast cancer cell lines. 4-[4′-(3,4-Dichlorophenoxy)-phenyl]-thiazol-2-yl ammonium iodide demonstrated potent activity against both estrogen-positive and negative breast cancer cell lines with low micromolar (μM) GI50 values. In addition, we have identified several 2-aminothiazoles that demonstrated selective potency for the adriamycin-resistant and estrogen-negative breast cancer cell lines. The results suggest that these 2-aminothiazoles represent lead compounds for evaluation in animal models of breast cancer.

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