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Usage

Uses

Used in Pharmaceutical Industry:
(4Z)-4-benzylidene-1-phenylpyrazolidine-3,5-dione is used as an active pharmaceutical ingredient for its anti-inflammatory and analgesic properties, targeting the treatment of various inflammatory conditions and pain management. Its potential efficacy in these areas makes it a promising compound for the development of new medications.
Used in Medicinal Chemistry Research:
(4Z)-4-benzylidene-1-phenylpyrazolidine-3,5-dione serves as a valuable subject for medicinal chemistry studies due to its unique structure and properties. Researchers can explore its potential for the development of novel drugs and therapies, particularly in the areas of inflammation and pain management.
Used in Synthetic Chemistry:
(4Z)-4-benzylidene-1-phenylpyrazolidine-3,5-dione's structure also makes it an important compound in synthetic chemistry. It can be utilized as a building block or a starting material for the synthesis of more complex molecules with potential applications in various fields, including pharmaceuticals, materials science, and chemical engineering.

Upstream product

• 100-63-0 phenylhydrazine 
• 19933-22-3 1-phenyl-pyrazolidine-3,5-dione 
• 100-52-7 benzaldehyde 

Downstream Products

• 353287-29-3 1-phenyl-3.5-dioxo-4-phenyliminomethyl-pyrazolidine 
• 1296783-86-2 1,2'-diphenyl-3,5-dioxo-1,2,3,5-tetrahydrospiropyrazole-4,3'-oxirane 
• 19933-22-3 1-phenyl-pyrazolidine-3,5-dione 
• 588-64-7 benzaldehyde phenylhydrazone 
• 54505-60-1 4-benzyl-1-phenyl-3,5-pyrazolidinedione 
• 13370-06-4 1,5-diphenyl-4-pyrazolin-3-one 
• 106584-28-5 1-phenyl-2-methyl-4-benzyliden-3,5-dioxopyrazolidine 
• 106584-33-2 1-phenyl-2,4-dimethyl-4-(α-methoxybenzyl)-3,5-dioxopyrazolidine 

Relevant academic research and scientific papers

Green synthetic investigation and spectral characterization of some spiro pyrazolidine-based heterocycles with potential biological activity

A green, rapid, and efficient methodology is developed for the synthesis of 1-phenyl-3,5-pyrazolidinedione (3) by the reaction of malonic acid with phenyl hydrazine in the presence of phosphorous oxychloride under solvent-free conditions. The later compou

Regioselective synthesis and anti-inflammatory activity of novel dispiro[pyrazolidine-4,3′-pyrrolidine-2′,3″-indoline] -2″,3,5-triones

Novel dispiro[pyrazolidine-4,3′-pyrrolidine-2′,3″- indoline]-2″,3,5-triones 5a-j were obtained regioselectively by 1,3-dipolar cycloaddition reaction of 4-arylidene-1-phenylpyrazolidine-3,5- diones 2a-e as dipolarophiles with non-stabilized azomethine yli

CHEMISTRY OF THE PYRAZOLIDINES. 26. ALKYLATION OF 4-BENZYLIDEN-1-PHENYL-3,5-DIOXOPYRAZOLIDINES

The reaction of 4-benzyliden-1-phenyl-3,5-dioxopyrazolidines with alkyl halides in the presence of sodium alkoxide gave 1-phenyl-2-alkyl-4-benzyliden- and 1-phenyl-2,4-dialkyl-4-(α-alkoxybenzyl)-3,4-dioxopyrazolines.The structures of these compounds were confirmed by UV, IR, and PMR spectroscopy, and by mass spectrometry.