130856-82-5

Upstream product

• 21090-30-2 3'-O-acetylthymidine 
• 84416-85-3 [5'-O-(4,4'-dimethoxytrityl)thymidine-3'-yl]-(N,N'-diisopropyl)methylphosphoramidite 
• 67-56-1 methanol 
• 151782-47-7 O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] O-methyl (O-4-nitrophenyl)-phosphate 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 364356-55-8 3'-O-acetyl-5'-O-(4,4'-dimethoxytrityl)-dithymidylyl-3',5'-phosphoroselenoate 
• 145498-72-2 5'-O-(4,4'-dimethoxytrityl)-thymidine-3'-O-(2-seleno-1,3,2-oxathiaphospholane) 
• 130277-22-4 (CH₃OC₆H₄)2C₆H₅COCH₃CO₂(C₅H₇OC₅N₂H₅O₂)2O₂POCH₃ 
• 151852-35-6 C₄₄H₄₉N₄O₁₄PS 

Downstream Products

• 87007-52-1 C₄₂H₄₇N₄O₁₄P 
• 160343-20-4 C₅₁H₅₇N₅O₁₉P₂ 
• 160343-28-2 C₃₀H₃₉N₅O₁₇P₂ 

Relevant academic research and scientific papers

Dithymidylyl-3',5'-phosphorofluoridates: New Synthesis and Stability under Solvolytic Conditions

Dithymidylyl-3',5'-phosphorofluoridates, prepared by nucleophilic substitution of methylselenyl by fluoride ion, are relatively unstable under solvolytic conditions and undergo rapid base-catalysed hydrolysis/methanolysis.

Rapid and efficient syntheses of phosphorylated dinucleotides

Nine or ten-step solution phase syntheses of the dimers dpApA, dApAp, dpTpT and dTpTp in 0.1-0.5 g amounts, in overall yields of 49%, 45%, 32%, and 20% respectively, are described. The synthetic intermediates were characterized by 1H and 3

EFFICIENT OXYGENATION OF THIOPHOSPHORYL AND SELENOPHOSPHORYL GROUPS USING TRIFLUOROACETIC ANHYDRIDE

Trifluoroacetic anhydride reacts with organophosphorus compounds containing thiophosphoryl and selenophosphoryl groups converting them in high yield to the corresponding oxygenated systems.