130865-70-2

Usage

Uses

Used in Pharmaceutical Industry:
2,3-Pyrrolidinedione, 4-methyl-1-(phenylmethoxy)is used as a building block in the synthesis of various pharmaceutical compounds due to its unique chemical structure and reactivity.
Used in Organic Synthesis:
2,3-Pyrrolidinedione, 4-methyl-1-(phenylmethoxy)is utilized as a key intermediate in organic synthesis, enabling the creation of a wide range of organic molecules for various applications, including the development of new drugs and other chemical products.
Used in Research and Development:
2,3-Pyrrolidinedione, 4-methyl-1-(phenylmethoxy)is used in research for its potential as a central nervous system stimulant, with ongoing studies aimed at understanding its properties and exploring its therapeutic potential in various medical applications.

Upstream product

• 622-33-3 N-benzyloxyamine 
• 70423-44-8 (Z)-4,4-Dimethoxy-3-methyl-crotonsaeureaethylester 
• 50331-71-0 ethyl 3-methyl-2-oxobut-3-enoate 
• 2687-43-6 O-benzylhydoxylamine hydrochloride 
• 132559-84-3 1-benzyloxy-3-hydroxy-4-methyl-2-pyrrolidinone 
• 67-68-5 dimethyl sulfoxide 
• 144564-41-0 4-Benzyloxyamino-3-methyl-butyric acid ethyl ester 
• 130865-74-6 4-[(E)-Benzyloxyimino]-3-methyl-butyric acid ethyl ester 
• 114839-28-0 4,4-Dimethoxy-3-methyl-butyric acid ethyl ester 
• 54998-57-1 ethyl 3-formylbutyrate 
• 130865-67-7 1-benzyloxy-4-methylpyrrolidin-2-one 

Downstream Products

• 130865-71-3 (R) 1-benzyloxy-4-methyl-2-oxo-3-(1-phenylethylamino)-2,5-dihydropyrrole 
• 130931-65-6 (3R,4R)-3-amino-1-hydroxy-4-methylpyrrolidin-2-one 
• 132695-96-6 3S-amino-1-hydroxy-4S-methylpyrrolidin-2-one 
• 130865-72-4 (3R,4R) 1-benzyloxy-4-methyl-3-<(R)-1-phenylethylamino>-2-pyrrolidinone 
• 130865-77-9 (3S,4S) 1-benzyloxy-4-methyl-3-<(R)-1-phenylethylamino>-2-pyrrolidinone 

Relevant academic research and scientific papers

A short and efficient synthesis of the NMDA glycine site antagonist: (3R,4R)-3-amino-1-hydroxy-4-methyl pyrrolidin-2-one (L-687,414)

A short and efficient synthesis of the NMDA glycine site antagonist: (3R,4R)-3-amino-1-hydroxy-4-methyl pyrrolidin-2-one (L-687,414) is described.

Routes to 4-Substituted Analogues of the Glycine/NMDA Antagonist HA-966. Enantioselective Synthesis of (3R,4R) 3-Amino-1-Hydroxy-4-Methyl-2-Pyrrolidinone (L-687,414).

Glycine anion (4) and glycine cation (8) synthons are used in efficient synthesis of 4-substituted analogues of HA-966 (1).A stereospecific route to cis derivatives involves hydrogenation of enamines such as 16.Introduction of a chiral auxiliary leads to

Hydrocarbon substituted pyrrolidinones, intermediates therefor, and anti-convulsant use thereof

Compounds of formula (I) and pharmaceutically acceptable acid addition salts thereof: STR1 wherein R represents a hydrocarbon group, X represents oxygen or sulphur, and R and --NH2 are cis; are of use in the treatment and/or prevention of neuro