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131036-39-0

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131036-39-0 Usage

Description

3-Bromo-5-Chloro-2-Picoline, also known as 3-Bromo-5-Chloro-2-Picoline, is an organic compound with the molecular formula C6H4BrClN. It is a derivative of picoline, a heterocyclic compound with a nitrogen atom in the ring structure. 3-Bromo-5-Chloro-2-Picoline is characterized by the presence of a bromine atom at the 3rd position and a chlorine atom at the 5th position on the pyridine ring. It is known for its potential applications in various industries due to its unique chemical properties.

Uses

Used in Pharmaceutical Industry:
3-Bromo-5-Chloro-2-Picoline is used as a reagent for the development of picomolar inhibitors of HIV reverse transcriptase. It is particularly effective in the creation of inhibitors featuring bicyclic replacement of the cyanovinylphenyl substructure. This application is significant in the fight against HIV/AIDS, as it aids in the development of potent and specific inhibitors that can effectively target the virus and limit its replication.

Check Digit Verification of cas no

The CAS Registry Mumber 131036-39-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,0,3 and 6 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 131036-39:
(8*1)+(7*3)+(6*1)+(5*0)+(4*3)+(3*6)+(2*3)+(1*9)=80
80 % 10 = 0
So 131036-39-0 is a valid CAS Registry Number.

131036-39-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-bromo-5-chloro-2-methylpyridine

1.2 Other means of identification

Product number -
Other names 3-bromo-5-chloro-2-picoline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:131036-39-0 SDS

131036-39-0Relevant articles and documents

MACROCYCLIC AZOLOPYRIDINE DERIVATIVES AS EED AND PRC2 MODULATORS

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, (2020/10/09)

The invention relates to modulators of Embryonic Ectoderm Development (EED) and/or Polycomb Repressive Complex 2 (PRC2) useful in the treatment of disorders and diseases associated with EEC and PRC2, being macrocyclic azolopyridine derivatives and compositions thereof of Formula (I), or a pharmaceutically acceptable salt, prodrug, solvate, hydrate, enantiomer, isomer, or tautomer thereof, wherein X1, X2, X3, A1, A2, Y, R1, R2, R3, and R4 are as described herein.

Compounds and their use as BACE Inhibitors

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Page/Page column 32, (2012/07/13)

The present invention relates to compounds of formula (I) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of Aβ-related pathologies such as Down's syndrome, β-amyloid angiopathy such as but not limited to cerebral amyloid angiopathy or hereditary cerebral hemorrhage, disorders associated with cognitive impairment such as but not limited to MCI (“mild cognitive impairment”), Alzheimer's disease, memory loss, attention deficit symptoms associated with Alzheimer's disease, neurodegeneration associated with diseases such as Alzheimer's disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration.

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