1311401-73-6

Basic information

• Product Name: 3-(2,2-diethoxyethoxy)-5,6-difluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline
• Synonyms: 3-(2,2-diethoxyethoxy)-5,6-difluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline
• CAS NO: 1311401-73-6
• Molecular Weight: 526.251
• Mol File: 1311401-73-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(2,2-diethoxyethoxy)-5,6-difluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,2-diethoxyethoxy)-5,6-difluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline(1311401-73-6)
• EPA Substance Registry System: 3-(2,2-diethoxyethoxy)-5,6-difluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline(1311401-73-6)

Safety Data

• Hazardous Substances Data: 1311401-73-6(Hazardous Substances Data)

Upstream product

• 29632-74-4 2-fluro-4-iodoaniline 
• 314-41-0 1,2,3,5-tetrafluoro-4-nitrobenzene 
• 765962-71-8 (2-fluoro-4-iodo-phenyl)-(2,3,5-trifluoro-6-nitro-phenyl)-amine 
• 621-63-6 glycoaldehyde diethyl acetal 
• 2367-82-0 1,2,3,5-tetrafluorobenzene 

Downstream Products

• 1311401-02-1 cyclopropanesulfonic acid [4,5-difluoro-6-(2-fluoro-4-iodophenylamino)-benzofuran-7-yl]-amide 
• 1311401-03-2 1-(2,3-dihydroxy-propyl)-cyclopropanesulfonic acid [4,5-difluoro-6-(2-fluoro-4-iodo-phenylamino)-benzofuran-7-yl]amide 
• 1311401-04-3 1-(2-hydroxyethyl)-cyclopropanesulfonic acid [4,5-difluoro-6-(2-fluoro-4-iodophenylamino)-benzofuran-7-yl]amide 
• 1311401-05-4 2-hydroxymethylcyclopropanesulfonic acid [4,5-difluoro-6-(2-fluoro-4-iodophenylamino)-benzofuran-7-yl]-amide 
• 1311401-74-7 (4,5-difluoro-7-nitro-benzofuran-6-yl)-(2-fluoro-4-iodo-phenyl)-amine 
• 1311401-75-8 4,5-difluoro-N₆-(2-fluoro-4-iodo-phenyl)-benzofuran-6,7-diamine 
• 1311401-76-9 4,5-difluoro-3-(2-fluoro-4-iodophenyl)-1H-benzofuro[6,7-d]imidazol-2(3H)-one 
• 1311401-77-0 1-(cyclopropylsulfonyl)-4,5-difluoro-3-(2-fluoro-4-iodophenyl)-1H-benzofuro-[6,7-d]imidazol-2(3H)-one 
• 1311401-78-1 1-(1-allylcyclopropylsulfonyl)-4,5-difluoro-3-(2-fluoro-4-iodophenyl)-1H-benzofuro[6,7-d]imidazol-2(3H)-one 
• 1415582-04-5 (R)-N-(4,5-difluoro-6-((2-fluoro-4-iodophenyl)amino)benzofuran-7-yl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide 
• 1415582-07-8 (R)-1-(2,3-bis(benzyloxy)propyl)-N-(4,5-difluoro-6-((2-fluoro-4-iodophenyl)amino)benzofuran-7-yl)cyclopropane-1-sulfonamide 
• 1415582-05-6 (S)-N-(4,5-difluoro-6-((2-fluoro-4-iodophenyl)amino)benzofuran-7-yl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide 
• 1311401-82-7 2-(benzyloxymethyl)-N-(4,5-difluoro-6-(2-fluoro-4-iodophenylamino)benzofuran-7-yl)cyclopropane-1-sulfonamide 
• 1311401-81-6 1-(2-(benzyloxymethyl)cyclopropylsulfonyl)-4,5-difluoro-3-(2-fluoro-4-iodophenyl)-1H-benzofuro[6,7-d]imidazol-2(3H)-one 

Relevant articles and documents

HETEROCYCLIC SULFONAMIDE DERIVATIVES

The present invention relates to compounds: and pharmaceutically acceptable salts thereof. The compounds have been demonstrated as inhibitors of MEK and therefore may be useful in the treatment of hyperproliferative diseases like cancer and inflammation.

HETEROCYCLIC SULFONAMIDE DERIVATIVES

The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The compounds have been demonstrated as inhibitors of MEK and therefore may be useful in the treatment of hyperproliferative diseases (e.g., cancer and inflammation).