1311458-36-2Relevant academic research and scientific papers
Synthesis toward Bivalent Ligands for the Dopamine D2 and Metabotropic Glutamate 5 Receptors
Qian, Mingcheng,Wouters, Elise,Dalton, James A. R.,Risseeuw, Martijn D. P.,Crans, René A. J.,Stove, Christophe,Giraldo, Jesús,Van Craenenbroeck, Kathleen,Van Calenbergh, Serge
, p. 8212 - 8225 (2018)
In this study, we designed and synthesized heterobivalent ligands targeting heteromers consisting of the metabotropic glutamate 5 receptor (mGluR5) and the dopamine D2 receptor (D2R). Bivalent ligand 22a with a linker consisting of 2
MACROCYCLIC COMPOUNDS FOR MODULATING IL-17
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Paragraph 00225, (2013/08/15)
The invention relates generally to macrocyclic compounds of formula I and their therapeutic use. More particularly, the invention relates to macrocyclic compounds that modulate the activity of IL-17 and/or are useful in the treatment of medical conditions
