131146-87-7Relevant articles and documents
Synthesis and in vitro anticancer activity evaluation of novel bioreversible phosphate inositol derivatives
Chen, Wenbin,Deng, Zhaohui,Chen, Kuangyu,Dou, Daolei,Song, Fanbo,Li, Luyuan,Xi, Zhen
, p. 172 - 181 (2015/03/05)
The chemistry and biology of phosphorylated inositols have become intense areas of research during the last two decades due to their involvement in various cellular signaling processes. However, the metabolic instability by phosphatases or kinases and poo
Synthesis of 3-Position-Modified Analogues of myo-Inositol 1,4,5-Trisphosphate, Tools for Investigation of the Polyphosphoinositide Pathway of Cellular Signaling
Liu, Changsheng,Potter, Barry V. L.
, p. 8335 - 8338 (2007/10/03)
Methods for the synthesis of 3-O-(carboxymethyl)- and 3-O-alkylated myo-inositol 1,4,5-trisphosphates in racemic form from myo-inositol have been devised. For DL-3-O-(carboxymethyl)-myo-inositol 1,4,5-trisphosphate, an analogue of myo-inositol 1,3,4,5-tet
Synthesis of (+/-)-3-O-Alkylated Myo-Inositol 1,4,5-Triphosphate Analogues as Potent Receptor Ligands and Enzyme Inhibitors
Liu, Changsheng,Potter, Barry V L
, p. 8457 - 8460 (2007/10/02)
The synthesis of novel analogues of myo-inositol 1,4,5-triphosphate alkylated at the 3-position from myo-inositol is described using a protection/deprotection sequence employing allyl, benzyl and p-methoxybenzyl groups.