58706-24-4

Basic information

• Product Name: (±)-3-O-benzyl-1,2:4,5-di-O-isopropylidene-myo-inositol
• CAS NO: 58706-24-4
• Molecular Weight: 350.412
• Mol File: 58706-24-4.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (±)-3-O-benzyl-1,2:4,5-di-O-isopropylidene-myo-inositol(CAS DataBase Reference)
• NIST Chemistry Reference: (±)-3-O-benzyl-1,2:4,5-di-O-isopropylidene-myo-inositol(58706-24-4)
• EPA Substance Registry System: (±)-3-O-benzyl-1,2:4,5-di-O-isopropylidene-myo-inositol(58706-24-4)

Safety Data

• Hazardous Substances Data: 58706-24-4(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 51548-88-0 (+/-)-1,2:4,5-di-O-isopropylidene-myo-inositol 
• 6404-82-6 (+/-)-1,2-O-isopropylidene-myo-inositol 
• 87-89-8 D-myo-inositol 
• 99756-37-3 (±)-3,6-di-O-benzoyl-1,2:4,5-di-O-isopropylidene-myo-inositol 
• 23486-90-0 (+/-) 1-O-benzyl-myo-inositol 
• 77-76-9 2,2-dimethoxy-propane 
• 108-24-7 acetic anhydride 
• 129094-34-4 Benzoic acid (3aR,4S,4aR,7aS,8S,8aR)-8-hydroxy-2,2,6,6-tetramethyl-hexahydro-benzo[1,2-d;4,5-d']bis[1,3]dioxol-4-yl ester 
• 111392-27-9 (+/-)-6-O-benzyl-1,2:4,5-di-O-isopropylidene-3-O-p-methoxybenzyl-myo-inositol 

Downstream Products

• 131146-88-8 (±)-1-O-allyl-4-O-benzyl-2,3-O-isopropylidene-myo-inositol 
• 131146-97-9 (1R,2S,3S,4R,5R,6S)-3,4,5-Tris-allyloxy-6-benzyloxy-cyclohexane-1,2-diol 
• 131146-96-8 (±)-2,3-O-isopropylidene-1,5,6-tri-O-allyl-4-O-benzyl-myo-inositol 
• 135182-39-7 (1S,2R,3S,4R,5S,6S)-2,3,4-Tris-allyloxy-5-benzyloxy-6-methoxymethoxy-cyclohexanol 
• 135182-40-0 (1R,2R,3S,4R,5R,6R)-3,4,5-Tris-allyloxy-2,6-bis-benzyloxy-cyclohexanol 
• 135182-41-1 {3-[Benzyloxy-((1S,2R,3R,4S,5S,6R)-2,6-bis-benzyloxy-3,4,5-trihydroxy-cyclohexyloxy)-phosphoryloxy]-propyl}-carbamic acid benzyl ester 
• 131146-87-7 (±)-4-O-allyl-1-O-benzyl-2,3;5,6-di-O-isopropylidene-myo-inositol 
• 131147-10-9 4,7,7-Trimethyl-3-oxo-2-oxa-bicyclo[2.2.1]heptane-1-carboxylic acid (3aS,4S,5R,6S,7S,7aS)-5,6,7-tris-benzyloxy-2,2-dimethyl-hexahydro-benzo[1,3]dioxol-4-yl ester 
• 131147-10-9 4,7,7-Trimethyl-3-oxo-2-oxa-bicyclo[2.2.1]heptane-1-carboxylic acid (3aR,4R,5S,6R,7R,7aR)-5,6,7-tris-benzyloxy-2,2-dimethyl-hexahydro-benzo[1,3]dioxol-4-yl ester 
• 131233-67-5 1,4,5,6-tetra-O-benzyl-2,3-isopropylidene-sn-myo-inositol 
• 131233-64-2 3,4,5,6-tetra-O-benzyl-1,2-isopropylidene-sn-myo-inositol 
• 131147-14-3 (+/-)-1,3,4,5-tetra-O-benzyl-myo-inositol 
• 261722-84-3 1,3,4,5-Tetra-O-benzyl-D-myo-inositol 
• 131147-14-3 1D-1,3,5,6-tetra-O-benzyl-myo-inositol 

Relevant articles and documents

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We have developed a novel class of synthetic molecular transporters that contain eight residues of guanidine with an inositol dimer as the scaffold. The dimers were prepared by connecting two units of myo- or scyllo-inositol via a carbonate or amide linkage, and the multiple units of the guanidine functionality were constructed on the inositol scaffold by means of peracylation with ω-aminocarboxylate derivatives of varying length. Bioassays based on confocal laser scanning microscopy and fluorescence-activated cell sorter analyses indicated that these transporters display a varying degree of membrane translocating ability, and the intracellular localization and mouse-tissue distribution studies strongly suggested that these transporters undergo substantially different mechanistic processes from those of peptide transporters reported to date. It was also shown that doxorubicin, an anticancer antibiotic, can be efficiently delivered into mouse brain by aid of this type of transporter.

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