131233-91-5

Basic information

• Product Name: methyl α-D-lyxopyranoside
• Synonyms: methyl α-D-lyxopyranoside
• CAS NO: 131233-91-5
• Molecular Weight: 164.158
• Mol File: 131233-91-5.mol
• Article Data: 68

Chemical Properties

• CAS DataBase Reference: methyl α-D-lyxopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl α-D-lyxopyranoside(131233-91-5)
• EPA Substance Registry System: methyl α-D-lyxopyranoside(131233-91-5)

Safety Data

• Hazardous Substances Data: 131233-91-5(Hazardous Substances Data)

Upstream product

• 3068-29-9 2,3,4-tri-O-acetyl-β-D-arabinosyl bromide 
• 7647-01-0 hydrogenchloride 
• 67-56-1 methanol 
• 56607-40-0 methyl D-arabinofuranoside 
• 50-69-1 D-ribose 
• 7473-45-2 1-O-methyl-D-ribofuranose 
• 10257-32-6 D-ribose 
• 87-72-9 L-(+)-arabinose 
• 5328-37-0 L-arabinose 
• 100924-40-1 2,3,4-tri-O-acetyl-L-arabinose 
• 5139-19-5 2,3,4,5-tetra-O-acetyl-L-arabinose 
• 16713-78-3 methyl 2-O-acetyl-3,4-O-isopropylidene-β-L-arabinopyranoside 
• 60-29-7 diethyl ether 
• 112346-33-5 methyl 2-O-p-tolylsulfonyl-β-L-arabinopyranoside 

Downstream Products

• 6638-76-2 methyl tri-O-benzoyl-α-D-arabinopyranoside 
• 4782-99-4 methyl-(O³,O⁴-isopropyliden-α-D-arabinopyranoside) 
• 66101-38-0 methyl-(O²,O³-((S)-benzylidene]-β-D-ribofuranoside) 
• 6638-76-2 methyl 2,3,4-tri-O-benzoyl-β-D-ribopyranoside 
• 14200-58-9 methyl 2,3,4-tris-(O-4-toluenesulfonyl)-β-L-arabinopyranoside 
• 6960-39-0 methyl 3,4-O-isopropylidene-β-L-arabinopyranoside 
• 5987-60-0 methyl O²,O⁴-phenylboranediyl-β-D-ribopyranoside 
• 5987-55-3 Methyl-β-L-arabinosid-<3,4-phenylboronat> 
• 34786-50-0 (R)-2-methoxy-2,2'-oxy-bis-acetaldehyde 
• 34786-50-0 (S)-2-methoxy-2,2'-oxy-bis-acetaldehyde 
• 87-72-9 D-Xylose 
• 242143-00-6 methyl 2,3,4-tri-O-benzyl-D-xylopyranoside 
• 77270-38-3 methyl 3,5-O-<(4-methoxyphenyl)ethylidene>-α-D-arabinopyranoside 
• 64-18-6 formic acid 

Relevant articles and documents

Regioselective mono-oxidation of non-protected glycosides by the bis-tributyltin oxide-bromide method

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SPINOSIDES A AND B. TWO CYTOTOXIC CUCURBITACIN GLYCOSIDES FROM DESFONTAINIA SPINOSA

Fractionation of the active ethanol extract of Desfontainia spinosa based on cytotoxicity has led to the discovery of three new derivatives of the parent compound, 11-deoxocucurbitacin I.The structures of 23,24-dihydro-11-deoxocucurbitacin I and the glycosides, spinosides A and B were elucidated on the basis of extensive analysis of their high field 1H NMR, 13C NMR, high resolution mass spectra (fast atom bombardment, field desorption, chemical ionization, electron impact) and chemical interconversions.Spinosides A and B were cytotoxic in the KB cell culture assay.

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Cleavage of 2-Phenyl-1,3-dioxolanes and Benzyl Ethers by Catalytic Transfer Hydrogenation

The selective deprotection of 2-phenyl-1,3-dioxolane derivatives and benzyl ethers of carbohydrates can be accomplished by catalytic transfer hydrogenation using hydrazine hydrate as hydrogen donor and 10percent palladium on carbon as catalyst.Under these conditions, 2-phenyl-1,3-dioxan and 2-alkyl substituted 1,3-dioxolane moieties remain unaffected.The proposed method is effective and the deprotected compounds are obtained in high yields.

New lignan glycosides with potent antiinflammatory effect, isolated from Justicia ciliata

Two new lignan glycosides, 4-O-[α-L-arabinopyranosyl-(1'''→2'')-β-D-xylopyranosyl-(1'''→5'')-β-D-ap iofuranosyl] diphyllin (1), named ciliatoside A (1), and 4-O-{[β-D-apiofuranosyl-(1''''→3''')-α-L-arabinopyranosyl-(1''''→2'')] [β-D-xylopyranosyl-(1''''→5'')]-β-D-apiofuranosyl}diphyllin (2), named ciliatoside B (2), were isolated from the whole plant of Justicia ciliata. The structures of 1 and 2 were determined by spectral and chemical methods. Compounds 1 and 2 strongly inhibited the accumulation of NO2- in lipopolysaccharide-stimulated RAW 264.7 cells in a concentration-dependent manner with IC50 values of 27.1 ± 1.6 and 29.4 ± 1.4 μM, respectively.

TWO IRIDOID GLYCOSIDES FROM REHMANNIA GLUTINOSA

Key Word Index - Rehmannia glutinosa var. hueichingensis; Scrophulariaceae; iridoid glycosides; iridoid arabinoside; iridoid rutinoside; jioglutosides.Abstract - Two new iridoid glycosides named jioglutosides A and B, together with 11 known iridoid glycosides, have been isolated from the fresh roots of Rehmannia glutinosa var. hueichingensis.On the basis of chemical and spectral analyses, the structures of jioglutosides A and B have been elucidated.

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Biosynthetic Origin of the Atypical Stereochemistry in the Thioheptose Core of Albomycin Nucleoside Antibiotics

Albomycins are peptidyl thionucleoside natural products that display antimicrobial activity against clinically important pathogens. Their structures are characterized by a thioheptose with atypical stereochemistry including a d-xylofuranose ring modified with a d-amino acid moiety. Herein it is demonstrated that AbmH is a pyridoxal 5′-phosphate (PLP)-dependent transaldolase that catalyzes a threo-selective aldol-type reaction to generate the thioheptose core with a d-ribofuranose ring and an l-amino acid moiety. The conversion of l-to d-amino acid configuration is catalyzed by the PLP-dependent epimerase AbmD. The d-ribo to d-xylo conversion of the thiofuranose ring appears according to gene deletion experiments to be mediated by AbmJ, which is annotated as a radical S-adenosyl-l-methionine (SAM) enzyme. These studies establish several key steps in the assembly of the thioheptose core during the biosynthesis of albomycins.

TRITERPENE SAPONIN SYNTHESIS, INTERMEDIATES AND ADJUVANT COMBINATIONS

The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.