131432-86-5Relevant academic research and scientific papers
A Chiral Synthesis of D-myo-Inositol 1-Phosphate Starting from L-Quebrachitol
Akiyama, Takahiko,Takechi, Naoto,Ozaki, Shoichiro,Shiota, Kenji
, p. 366 - 372 (2007/10/02)
A naturally occurring optically active cyclitol, L-quebrachitol (1L-2-O-methyl-chiro-inositol), was stereoselectively transformed into myo-inositol derivatives via an oxidation-reduction process.The methyl ether was cleaved chemoselectively with AlCl3NaI
A concise synthesis of (-)-conduritol F from L-quebrachitol via AlCl3-n-Bu4NI mediated demethylation
Akiyama, Takahiko,Shima, Hiroaki,Ozaki, Shoichiro
, p. 5593 - 5596 (2007/10/02)
(-)-Conduritol F was prepared starting from naturally occurring cyclitol, L-quebrachitol, in 5 steps via AlCl3-Bu4NI mediated chemoselective demethylation of the methyl ether. A preparation of (+)-conduritol B was also described.
Anchimerically Assisted Demethylation of Methyl Ethers in Inositol Derivatives with an AlCl3-NaI System
Akiyama, Takahiko,Takechi, Naoto,Shima, Hiroaki,Ozaki, Shoichiro
, p. 1881 - 1884 (2007/10/02)
Investigated are AlCl3 and NaI catalyzed chemoselective demethylation reactions of methyl ethers of partly protected inositol derivatives, reactions which are greatly promoted by vicinal OH group and proceed in preference to the cleavage of the cis cyclohexylidene moiety.
Chiral synthesis of D-Myo-inositol 1-phosphate starting from L-querbrachitol
Akiyama,Takechi,Ozaki
, p. 1433 - 1434 (2007/10/02)
D-Myo-inositol 1-phosphate was synthesized from L-quebrachitol via stereoselective inversion of a 3-hydroxyl group and chemoselective demethylation.
